This is an Application Brief and does not contain a detailed Experimental section.
This application brief highlights Oasis sample extraction products chemistry and formats
The patented design of the Oasis family of solid-phase extraction products, along with a diverse selection of chemistries and formats, provide bioanalytical scientists with the needed selectivity to achieve the sensitivity that their assays require.
Oasis HLB is a hydrophilic-lipophilic-balanced, water-wettable, reversedphase sorbent for all your SPE needs. It is made from a specific ratio of two monomers, hydrophilic N-vinylpyrrolidone and lipophilic divinylbenzene. It provides superior reversed-phase capacity with a neutral polar ‘hook’ for enhanced retention of polar analytes.
Water-wettable Oasis sorbents exhibit excellent retention capacity for a wider polarity spectrum of analytes, even if the sorbent bed runs dry during conditioning or sample loading. This means that your SPE methods will be more rugged and robust, precluding the need for repeat sample preparation.
Oasis MCX, for basic compounds, provides dual modes of retention— cation exchange, and reversed phase—on a single, clean, stable, high-surface-area, organic co-polymer that is stable from pH 0-14. The ability to fully manipulate pH during the development, optimization, and use of SPE methods on mixed-mode sorbents enables not only fast, straightforward-method development, but also ensures very rugged and robust procedures.
Oasis MAX is a strong mixed-mode anion-exchange, water-wettable, polymeric sorbent stable from pH 0-14. Now you can employ reliable SPE in methods to detect, confirm, or quantify acidic compounds and/or acidic metabolites in biological fluids. SPE procedures using the selectivity and ruggedness of Oasis MAX sorbent enable separation of analytes from complex matrices.
The Oasis WCX sorbent is designed to provide superior sample preparation for strong bases and quaternary amines. It is a weakcation- exchange, mixed-mode, water-wettable, polymeric sorbent, stable from pH 0-14. Rugged and highly selective SPE methods using Oasis WCX sorbent detect, confirm, and quantify strongly basic compounds and quaternary amines in biological fluids.
The Oasis WAX sorbent is designed to provide superior sample preparation for strong acids. It is a weak-anion-exchange, mixed-mode, water wettable, polymeric sorbent, stable from pH 0 to 14. Rugged and highly selective SPE methods using Oasis WAX detect, confirm, and quantify strongly acidic compounds in biological fluids.
720003678, September 2010