This is an Application Brief and does not contain a detailed Experimental section.
This application brief demonstrates analysis of Succinimides.
The compounds used in this study are -
| 
                     Compounds  | 
                     USP Tailing Factors  | 
            
|---|---|
| 
                     Ethosuximide  | 
                     0.96  | 
            
| 
                     Phensuximide  | 
                     0.92  | 
            
| 
                     Methsuximide  | 
                     0.91  | 
            
            
        | 
                     Column:  | 
                     Symmetry C8, 3.9 x 150 mm, 5 μm  | 
            
| 
                     Guard column:  | 
                     Sentry Guard Column 3.9 x 20 mm, 5 μm  | 
            
| 
                     Part numbers:  | 
                     Column - WAT046970, Guard - WAT054250  | 
            
| 
                     Mobile phase:  | 
                     100 mM potassium phosphate, pH 6.9/methanol/water 20:30:50  | 
            
| 
                     Flow rate:  | 
                     1.0 mL/min  | 
            
| 
                     Injection volume:  | 
                     10 μL of 40–500 μg/mL sample  | 
            
| 
                     Detection:  | 
                     UV @ 214 nm  | 
            
            
        WA31763.153, June 2003