DMPK workflows, not workarounds

Don’t just migrate with existing systems — modernize to end‑to‑end DMPK solutions deliberately designed to work as one across small molecules, large molecules, and emerging modalities.​

Adopting the Waters suite of bioanalysis tools is the opportunity to:

  • Simplify discovery and development decisions using tools designed to work together seamlessly​. With Waters, you can integrate DMPK data, advanced analytics, and regulatory‑aligned insights while reducing variability across studies and programs. ​
  • Eliminate non‑specific adsorption with confidence from the very first injection​, minimize analyte loss, and remove the need for time‑ and sample‑consuming passivation steps without worrying about analyte loss — ensuring reproducibility, even at the lowest concentrations.
  • Ensure continuous confidence in DMPK outputs backed by secure, compliant-ready informatics platforms. Build audit readiness, data integrity, and full traceability directly into routine study execution, and operate resilient, scalable DMPK workflows designed for maximum productivity.
3d rendering of colorful digital mesh network on blue background
Pipettes dropping liquid into well plate

Why teams like yours choose Waters

Paul Holme smiling at camera
“We processed 10,000+ challenging samples while meeting regulatory demands — day‑in, day‑out.”
— Paul Holme,  Synexa Life Sciences
Xevo TQ Absolute XR Logo Closeup
“Recently for [our] oligonucleotide project, we decided to adopt the ACQUITY Premier UPLC System toprevent NSB [non-specific binding]. . .  Overall, the performance and quality of Waters new TQ system [Xevo TQ Absolute XR Mass Spectrometer] are widely recognized in the market, and this is precisely why we ultimately chose your solutions."
— Mr. Cheng Lou, Sr. Director, Bioanalysis Department, Medicilon​
In Conversation — Q&A​

Purpose-built to work across all modalities

Analyze small molecules, peptides, proteins, and oligonucleotides — without reinventing your methods. As therapeutic modalities become more complex, your lab can gain efficiency and confidence with complete workflows, not workarounds.​

Simple line drawing of the Andrew+ Pipetting Robot

Automation

Automation
  • Andrew+ Robot
  • Extraction+
line drawing of test tubes connected by a line

Sample Preparation

Sample Preparation
  • Oasis SPE Kits
  • OligoWorks Kit
  • RapiZyme Trypsin
Simple line drawing of the Alliance iS system

Separation

Separation
  • MaxPeak HPS Columns
  • ACQUITY Premier System
Simple line drawing of the Xevo TQ Absolute XR

Identification and Quantitation

Identification and Quantitation
  • Xevo TQ Absolute XR Mass Spectrometer
line drawing of a lap top with a chart on it

Data Processing and Review

Data Processing and Review
  • waters_connect for Quantitation

Consistent tools across multiple modalities simplifies the process

Consistent tools across multiple modalities simplifies the process
Download DMPK eBook

Simplify discovery and development bioanalysis

Reduce friction and simplify daily execution with an integrated, standardized DMPK workflow​.

  • 30 years of trusted SPE performance: Oasis HLB Kits with pre‑optimized protocols to simplify method development. ​
  • Chromatography without worries: MaxPeak Premier Columns for consistent chromatography and ACQUITY Premier System to minimize metal‑sensitive headaches. ​
  • Class‑leading quantification without constant cleaning: Xevo TQ Absolute XR Mass Spectrometer delivers robustness at scale — engineered for regulated bioanalysis.​
  • Compliant-ready informatics platforms: Bring audit trails, e‑signatures, granular user roles, and Exception Focused Review (XFR) together in waters_connect for Quantitation Software — built to keep you inspection‑ready without slowing down study execution.

Download the infographic to see a simpler, faster way to run oligonucleotide bioanalysis.​

Download Infographic
Aerial shot of various pills scattered out of white bottle

Ensure continuous confidence

Standardize methods once — then seamlessly transfer between instruments and labs.​

  • Keep workflows constant across modalities: Minimize rework when switching between projects.
  • Reduce review time with Exception Focused Review (XFR): waters_connect for Quantitation Software flags what needs attention — saving up to 50% on data evaluation time.
  • Lock in uniform methods and minimize training demands: An informatics platform that scales across TQ and HRMS systems for discovery and development studies.

See how consistency scales to meet the demands of your operations.​

Watch Webinar

Make your next migration your last

With guided upgrades that de‑risk change and future‑proof your lab, Waters experts are here to support you in every step of your DMPK workflow. Partner with Waters to leverage:​

  • Informatics Professional Services for validation, documentation best practices, and regulatory alignment.
  • Analytical and Laboratory Services for method transfer, validation, and application consultation​.
  • Modernize aging assets with minimal disruption with the FlexUP Technology Replacement Program.
  • Experienced scientific teams that understand the technology and your workflows to help maximize impact and minimize delays​.
White and blue pills in blister packs

Find out how Waters solutions can simplify, standardize, and accelerate your DMPK studies.​

Back To Top Back To Top