The Waters GTxResolve 2000 Å SEC column, MaxPeak Premier 3 µm is designed with low-adsorption MaxPeak hardware and advanced bridged ethylene HO-PEO particles. This innovative composition ensures high recovery for GTx drugs ranging from 800 to 2500 Å in diameter, including lipid nanoparticles (LNPs), plasmids, and viral vectors. Engineered for extended column lifetimes, minimal secondary interactions, and enhanced MALS sensitivity, this solution supports the development of multi-attribute platform methods. It enables comprehensive integrity and heterogeneity analyses of LNP formulations, plasmid topology assessments, and improved detection of ejected transgenes and aggregates in viral vector applications.
|
Química |
SEC |
|
Modo de separación |
SEC |
|
Sustrato de partículas |
Silica |
|
pH Range Min |
2.5 pH |
|
pH Range Max |
8 pH |
|
Temperature Limits |
60 C |
|
Maximum Pressure |
2000 psi (140 Bar) |
|
Endcapped |
No |
|
Tecnología de enlazado |
SEC |
|
Silanol Activity |
Low |
|
Particle Shape |
Spherical |
|
Tamaño de partícula |
3 µm |
|
Endfitting Type |
Parker-style |
|
Tamaño de poro |
2000 Å |
|
Formato |
Columna Premier |
|
Área de superficie |
19 |
|
Sistema |
UHPLC, UPLC, HPLC |
|
Tecnología de partículas |
Sílice |
|
Technique |
SEC |
|
Clasificación USP |
L33 |
|
Diámetro interno |
4.6 mm |
|
Longitud |
150 mm |
|
Carbon Load |
1.2 % |
|
UNSPSC |
41115709 |
|
Aplicación |
Gene Therapeutics |
|
Marca |
GTxResolve |
|
Tipo de producto |
Columnas |
|
Units per Package |
1 pk |
|
eConnect |
No |