- Bacterial endotoxin testing (BET) — VLF/HEPA configuration ensures contamination-free environment for kinetic chromogenic (LAL) and recombinant Factor C assays at sub-nanogram sensitivity
- ELISA and plate-based immunoassays — HEPA-protected automation for consistent, contamination-free assay execution
- Forensic and clinical toxicology SPE — ABEK configuration shields users from organic solvents (methanol, acetonitrile) during Oasis SPE extractions from blood, urine, or plasma
- Immunosuppressant therapeutic drug monitoring — automated sample prep with user protection from volatile solvents used in protein precipitation and SPE workflows
- Bioanalytical DMPK sample preparation — ABEK-protected automation for high-throughput plasma extraction workflows involving organic solvents prior to LC-MS/MS analysis
Andrew+ Pod
Andrew+ Pod
The Andrew+ Robot Experience. Elevated.
The Andrew+ Robot Experience. Elevated.
Meet the Andrew+ Pod. Where cutting-edge technology meets unparalleled convenience.
The Andrew+ Pod is a purpose-built, compact benchtop enclosure for the Andrew+ Robot. It provides sample and/or user protection through interchangeable air filtration modules , while maintaining the full Andrew+ deck
Five configurations available:
- Andrew+ Pod — Enclosed workspace with hardware interlock, optimized cable management, and deeper tip waste
- With Onboard Ventilation Module — Active airflow for heat-sensitive experiments
- Vertical Laminar Flow (VLF) with HEPA H14 — ISO Class 5 clean air protecting samples from particulate contamination (99.995% filtration efficiency ≥ 0.3 µm)
- Recirculatory Filtration Fume Cabinet (RFFC) with ABEK — Ductless user protection from harmful organic, inorganic, acid gases, and ammonia derivatives (ISO EN 14175-3)
- External Duct Adaptor — Connects to existing lab air-extraction infrastructure
Key features across all configurations:
- Hardware interlock with zero-access policy during operation
- Environmental monitoring (temperature, humidity, atmospheric pressure, VOC)
- Interchangeable side panels for Automation Portal+ and Plate Sealer+ integration
- Control of motorized sash for cobot/mobile robot integration
Andrew+ Pod
Overview
- Protect your samples with vertical laminar flow and HEPA H14 filtration
- Protect users from harmful gases with a standalone air filtration solution
- Add the Andrew+ Pod to your existing air-extraction infrastructure
- Access the Andrew+ Robot only when not in use, ensuring user safety at all times
- Integrate the Andrew+ Pod into your workflows using OneLab Software API controls, enabling additional automation such as mobile robots or cobots
- Interchange side panels to quickly and easily adapt the enclosure to include external devices, such as the Plate Sealer+ and Waters ACQUITY UPLC Systems
- Achieve optimal working conditions for the Andrew+ Robot even if your workbench isn’t perfectly flat
- Work with up to 11 Dominos and Connected Devices – the maximum possible Andrew+ Pipetting Robot configuration
Recommended Use: Dedicated enclosure for the Andrew+ Robot, designed to bring indispensable air-filtration capabilities for various sample preparation settings.
Andrew+ Pod Configurations and Components
Andrew+ Pod Configurations and Components
Andrew+ Pod
-
Optimized cable management -
Hardware interlock for user and method safety
-
Dust protection
-
Interchangeable side-panel access
-
Deeper, more accessible tip waste.
Andrew+ Pod with Onboard Ventilation Module
-
Optimized cable management
-
Hardware interlock for user and method safety
-
Dust protection
-
Interchangeable side-panel access
-
Deeper, more accessible tip waste
-
Active temperature management for heat-sensitive experiments.
Andrew+ Pod Vertical Laminar Flow (VLF) Enclosure with HEPA Filter
-
Optimized cable management
-
Hardware interlock for user and method safety
-
Dust protection
-
Interchangeable side-panel access
-
Deeper, more accessible tip waste
-
HEPA H14 Filtration Vertical Laminar Flow.
Andrew+ Pod Recirculatory Filtration Fume Cabinet (RFFC) with ABEK Filter
-
Optimized cable management
-
Hardware interlock for user and method safety
-
Dust protection
-
Interchangeable side-panel access
-
Deeper, more accessible tip waste
-
Onboard (ductless) system for harmful gas removal can be installed in various locations.
Andrew+ Pod with External Duct Adaptor Module
-
Optimized cable management
-
Hardware interlock for user and method safety
-
Dust protection
-
Interchangeable side-panel access
-
Deeper, more accessible tip waste
-
Enables physical connectivity to existing lab air-filtration infrastructure.
Less clutter, less waste, less user intervention
When connected to the Andrew+ Pod, the Andrew+ Robot uses a large-capacity tip waste ideal for long automation runs. After the Andrew+ Robot finishes, solid waste removal is easy due to its convenient position at the front of the Andrew+ Pod.
With the Andrew+ Pod, you can effortlessly organize and put away the cables and power bricks needed for your devices (including the tubing required for the Extraction+ Device) – making for a clean and tidy automation workbench you’ll want to show off.
Capture experimental conditions and validate results
The Andrew+ Pod features sensors that gather essential metadata to ensure experimental conditions are met. This includes real-time measurements of temperature, humidity, atmospheric pressure, and VOC saturation. This data is displayed via OneLab Software and stored in each experiment record for future reference.
Easy to install, intuitive to use
Install the Andrew+ Pod in three easy steps
Take the Andrew+ Pod out of the box and position it on your designated bench space. Adjust the feet and position your ventilation module with filters according to your desired configuration. Connect The Andrew+ Robot through a simple port and follow the on-screen configuration instructions in OneLab Software.
That’s all it takes. Once installed, you control The Andrew+ Robot with a sleek three-button panel to manage power, the motorized sash, fan speeds, and LED lighting. Synchronized colored notifications provide instant status updates, making errors easy to spot.
Waters can install and validate this total automated solution — the Andrew+ Robot, the Andrew+ Pod, and OneLab Software — in just two days.
Interchangeable side panels: Endless possibilities.
The Andrew+ Pod is designed to enable complex workflows without compromising the core functions of the enclosure or the Andrew+ Pipetting Robot. Interchangeable side panels allow users to quickly and easily adapt their enclosed automation setup to external devices, such as the Plate Sealer+ and ACQUITY UPLC, via the Automation Portal+ for extended workflows.
Going beyond physical integrations
The OneLab Software works hand in hand with the waters_connect Platform, Empower Software, or MassLynx Software to deliver fully integrated data acquisition and truly end-to-end automation.
The Andrew+ Pod integrates seamlessly into sample-to-result workflows, with OneLab Software API controls enabling automations such as opening the motorized sash for handoffs to mobile robots or cobots.
Applications
- Peptide mapping — ABEK configuration protects users from organic solvents and acids (acetonitrile, formic acid, TFA) used during reduction, alkylation, and digestion
- Protein precipitation — user protection during automated crash workflows using methanol or acetonitrile for DMPK and PK/TK studies
- Amino acid analysis (AccQ•Tag Ultra) — ABEK-protected automation of derivatization with organic reagents for accurate amino acid quantification
- Biosimilar glycan analysis — HEPA-protected sample preparation for glycan release, labeling, and clean-up prior to LC-FLR/MS analysis
- SP3 and S-Trap proteomics workflows — controlled environment for bead-based protein clean-up and tryptic digestion
- Routine SPE with organic solvents — ABEK protection for everyday solid phase extraction workflows using methanol, acetonitrile, or ethyl acetate
- Serial dilutions and standard curve preparation — enclosed, controlled environment for improved reproducibility and reduced contamination risk
- LC-MS sample preparation with volatile solvents — user protection during reconstitution and transfer steps involving organic mobile phases
- Sample aliquoting and reformatting — dust-free, enclosed workspace for consistent plate-to-plate and tube-to-plate transfers
- Walk-away overnight runs — hardware interlock and environmental monitoring ensure safe, unattended operation during extended protocols
Resources
Documents
Documents
Support
Support
What do you want to do?
What do you want to do?
Need Help?
Frequently Asked Questions
Frequently Asked Questions
What is the Andrew+ Pod?
A purpose-built, compact benchtop enclosure for the Andrew+ Pipetting Robot. It provides sample protection, user protection, or both — depending on the filtration configuration — while maintaining the full Andrew+ deck (up to 11 Dominos and connected devices). It connects directly to the Andrew+ Waste Domino via CAN bus and is fully controlled through OneLab.
What configurations are available?
- Andrew+ Pod — Enclosed workspace with hardware interlock, optimized cable management, dust protection, and deeper tip waste
- With Onboard Ventilation Module — Active airflow for heat-sensitive experiments
- Vertical Laminar Flow (VLF) with HEPA H14 — ISO Class 5 clean air; removes 99.995% of particles ≥ 0.3 µm; protects samples from particulate contamination
- Recirculatory Filtration Fume Cabinet (RFFC) with ABEK — Ductless user protection from organic, inorganic, acid gases, and ammonia derivatives (tested to ISO EN 14175-3)
- External Duct Adaptor — Connects to existing lab air-extraction infrastructure
Does the VLF/HEPA configuration replace a biosafety cabinet?
No. The Andrew+ Pod with VLF/HEPA is a downflow cabinet providing ISO Class 5 clean air for sample protection. It is not a biological safety cabinet (BSC) and does not provide user protection from biological hazards. It is designed for contamination-sensitive applications such as endotoxin testing.
Has the filtration performance been independently tested?
Yes. Both the HEPA and ABEK configurations were tested by SKAN AG (Switzerland), a global leader in isolator and cleanroom testing. The VLF/HEPA configuration achieved ISO Class 5 under ISO 14644-1, including with Andrew+ operating inside. The RFFC/ABEK configuration achieved CP2 containment performance under ISO EN 14175-3.
Can I switch between HEPA and ABEK filters?
Yes. The ventilation system is the same across configurations. You can swap the HEPA H14 filter for an ABEK filter (or vice versa) and update the configuration in OneLab. This allows a single Pod to serve both sample-protection and user-protection workflows.
How does the hardware interlock work?
The Andrew+ Pod enforces a zero-access policy — physical access to the robot and Domino deck is only granted when Andrew+ is not in motion. If user interaction is needed mid-run, you can embed a user action step in the OneLab protocol or pause via the Pod's onboard controls. The sash will only open when it is safe to do so.
What environmental data does the Andrew+ Pod record?
The Pod continuously monitors and logs temperature, humidity, atmospheric pressure, and VOC levels. This metadata is captured alongside the experiment data in OneLab for full traceability.
Can I use connected devices inside the Andrew+ Pod?
Yes. The Pod supports the full Andrew+ ecosystem, including Extraction+, Shaker+, Heater-Shaker+, Peltier+, Magnet+, Plate Sealer+, and grippers. Interchangeable side panels allow integration with Automation Portal+ (for LC/LC-MS walkup) and Plate Sealer+.
Can the Pod integrate with external automation (cobots, mobile robots)?
Yes. The motorized sash can be controlled via the OneLab API, enabling integration with cobots, mobile robots, or scheduling software (e.g., Biosero Green Button Go) via OneLab Enterprise.
What are the key technical specifications?
- Dimensions: 112 × 81 × 82.8 cm (max height 139.8 cm with sash open)
- Weight: 44 kg (Pod) / 5.8 kg (Ventilation Module)
- Minimum benchtop: 106 cm (W) × 57 cm (D)
- Power: 85–264 VAC, 47–63 Hz
- Operating temperature: +4°C to +37°C
- Operating humidity: ≤ 80% RH (up to 31°C)
- Fan noise: 56 dB(A) at 1 m (max speed)
- Interface: CAN bus to Andrew+ Waste Domino
- Protection: IP 20
- VLF airflow speed: 0.20 m/s
- Warranty: 1 year
- How often should filters be replaced?
- HEPA H14 — Every 12–18 months
- ABEK — Every 6–12 months (depending on chemicals used and intensity)
- Pre-filter — Replace with every HEPA or ABEK change
Related
Transform manual pipetting into a fully automated, error-free liquid handling system with the Andrew+ Pipetting Robot, powered by OneLab Software.
Design, execute, and track lab experiments with OneLab Software, secure cloud-based platform for protocol automation, traceability, and collaboration.
Simplify SPE workflows with Extraction+ Device, delivering consistent, reproducible results with smart pressure profiling, broad labware compatibility, and seamless Andrew+ Robot integration.
