• Application Note

Procainamides at pH 6.0

Procainamides at pH 6.0
  • Waters Corporation
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This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief highlights the analysis of Procainamides at pH 6.0 using Symmetry columns.

 

Introduction

Compounds used in this application brief includes Procainamide, N-Acetylprocainamide, and N-Propionylprocainamide.

Experimental

HPLC Method

Column:

Symmetry C8, 3.9 x 150 mm, 5 μm (p/n: WAT046970)

Mobile phase:

20 mM potassium phosphate, pH 6.0/acetonirtrile 90:10

Flow rate:

1.0 mL/min

Injection volume:

10 μL of 40 μg/mL each compound

Detection:

UV @ 254 nm

USP tailing factors:

1. 1.4

2. 1.4

3. 1.4

Results and Discussion

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WA31763.129, June 2003

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