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Nimodipine and Impurities Scale-up

Nimodipine and Impurities Scale-up
  • Waters Corporation
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Brain hemorrhage or stroke

This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief highlights the scaling-up of nimodipine and its impurities.

Introduction

Nimodipine is used to treat symptoms resulting from a ruptured blood vessel in the brain (hemorrhage). It increases blood flow to injured brain tissue.

Experimental

Conditions

Column:

SunFire C18 4.6 x 100 mm, 5 μm (p/n: 186002558)

19 x 100 mm, 5 μm (p/n: 186002567)

Mobile phase A:

Water with 0.1% FA

Mobile phase B:

ACN with 0.1% FA

Flow rate:

1 mL/min

Injection volume:

10 μL

Detection:

UV @ 290 nm

Instrument:

Waters AutoPurification System

Results and Discussion

Featured Products

WA41896, May 2005

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