Small Molecule Research and Discovery

Minimize metal-sensitive analyte loss and improve recovery with the ACQUITY Premier System for ultra-performance liquid chromatography, delivering a step change in chromatographic performance, lab efficiency, and risk control.

Generate the most accurate, reliable, and reproducible data with the Arc Premier System for robust results from the very first injection.

With industry-leading separations performance, the ACQUITY UPLC I-Class PLUS System provides new possibilities for maximizing the resolution and sensitivity of your methods, enhancing the characterization of your samples, and improving productivity to advance the science of your laboratory.

Achieve the performance you expect from nano- to microscale separations with the usability of an analytical-scale UPLC system with the ACQUITY UPLC M-Class System, designed and tested to deliver the right flow for the right column. 

Gain absolute confidence to make powerful decisions and reach lower limits of quantitation with the Xevo TQ Absolute XR Mass Spectrometer, engineered for maximum sensitivity and productivity in a compact, sustainable design.

Maximize sample information for your analytes from detailed characterization to accurate quantitation with the Xevo G3 QTof System, which enables complete confidence in your results.

Obtain 100K FWHM resolution at 100 Hz with sub-ppm mass accuracy with the Xevo MRT Mass Spectrometer for mass resolution consistent over a broad m/z range independent of scan speed, even at the fastest acquisition rates. 

Combining novel cyclic ion mobility separation with state-of-the-art, high-performance, time-of-flight mass spectrometry, the SELECT SERIES Cyclic IMS Systen unlocks the potential in scientific discovery.

Easy to use and remarkably robust, the ACQUITY QDa II Mass Detector works in harmony with your chromatography to minimize the risk of unexpected components or coelutions and confirm trace sample constituents in a single workflow.

Achieve uncompromised analysis of both low and high molecular weight species with a wide mass range with the SQ Detector 2, enabling versatile chromatographic options to ensure compatibility with all of your applications. 

Increase productivity, improve data confidence, and simplify routine accurate mass workflows with the compact, compliance-ready and easy-to-use ACQUITY RDa Detector.

Equip your lab with Empower Chromatography Data System (CDS) and gain advanced laboratory data management for your small molecule analyses, including acquisition, processing, and reporting for liquid and gas chromatography instruments.

Maximize your productivity with compliant-ready solutions for the analysis of compounds like drugs of abuse, metabolites, impurities, extractables, and leachables with waters_connect for Small Molecule Workflows. 

See all of your sample with MaxPeak Premier Columns, the most universal column platform for chromatographers who need to reduce variability risks and save time, all while increasing recovery and sensitivity.

Avoid analyte degradation of pH sensitive samples with Waters TruView pH Control LCMS Certified low adsorption vials, the only vials tested and certified for low analyte adsorption at 1 ng/mL and a maximum pH shift.

Optimize your laboratory's productivity and success with Waters Global Services. Maintain peak system performance, minimize downtime, address application challenges, and support stringent compliance requirements.

Maximize your lab resources and minimize risk with innovative solutions and payment options from Waters Capital. Upgrade aging instruments, obtain customized support, and gain flexible options to bundle your complete laboratory solution into one easy monthly payment – everything you need to advance your science.