MassTrak ACQUITY UPLC I-Class PLUS/Xevo TQ Absolute XR IVD System
Absolute confidence for challenging compounds in the clinical laboratory
With energy costs rising, laboratory space at a premium, and growing pressure to reduce send-out testing, clinical laboratories need an analytical system that supports complex trace analyte quantification in-house while helping reduce energy use and save valuable lab space. The MassTrak ACQUITY UPLC I-Class PLUS/Xevo TQ Absolute XR IVD System is a compact, sustainable solution designed to accurately quantify trace analytes, while supporting better patient care, cost savings, and laboratory-specific workflow needs through a range of customizable options.
The Xevo TQ Absolute XR IVD Mass Spectrometer, delivers the confidence to make critical decisions, perform complex trace analyte quantification , and maintain optimum sensitivity for longer periods of operation compared to previous systems. Engineered for productivity in a compact, sustainable design, it features the StepWave XR Ion Guide for enhanced resistance to contamination from high-throughput, complex sample matrices, helping maximize uptime, reduce interventions, and deliver the robust performance clinical laboratories can trust while supporting environmental, social, and governance goals.
Overview
- Performance and sensitivity: Achieve up to 6x more robustness1 with the StepWave XR Ion Guide, designed to resist contamination from clinical matrices and deliver consistent performance.
- Confidence for difficult analytes: Gain up to 15x greater sensitivity2 for challenging negative-ion compounds to support confident quantification at clinically relevant decision points.
- Operational efficiency: Support more sustainable lab operations with a footprint about 45% smaller than leading competitors, about 50% lower electricity and gas consumption, reduced heat output, and ACT Ecolabel bronze certification.
- Informatics and control: Manage system access, monitor instrument status, and process and review results efficiently with intuitive software solutions.
- Maintenance simplicity: Save time and support reproducible results with tool-free maintenance protocols.
- Workflow integration: Improve data flow through connectivity with liquid handling robots and the HL7-compliant MassLynx LIMS Interface.
- Service support: Maintain uptime with FlexCHOICE: mySystem Coverage solutions, including a call back within 2 hours, 48-hour on-site response, and priority support.
1,2 Refer to Xevo TQ Absolute XR Triple Quadrupole Mass Spectrometer for supporting data.
Recommended Use: For the analysis and quantification of low-concentration analytes and improved application selectivity in the clinical lab.
Features Header
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Improve productivity and save time by connecting multiple columns that automatically switch based on the analysis being performed
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Ideal for dedicating your system to a single type of analysis and achieving workflow requirements
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Ideal for analyzing a large number of samples
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Large capacity to help keep your analysis running when you’re away by automatically introducing plates into the instrument for analysis
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Sample injection versatility for your applications
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Maximize injection volume range from 0.1 to 1000 µL with a needle-in-flow path injector
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Shortest inject-to-inject cycle times with a loop-based injector
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Programmable method settings and ultra-low carryover for compatibility with the most sensitive mass spectrometers
Ensure absolute confidence with eXtreme robustness
The Xevo TQ Absolute XR IVD Mass Spectrometer provides up to six times greater robustness than the Xevo TQ Absolute Mass Spectrometer before service maintenance is required with a unique design to resist contamination from real clinical matrices. This is one example of more than 30,000 injections of naltrexone and metabolites in human plasma.
Naltrexone and its metabolite 6b-Naltrexol were extracted from human plasma with a simple protein precipitation and analyzed on the Xevo TQ Absolute XR IVD Mass Spectrometer and the study indicated that 30,000 injections were within the calculated concentration limits of +/- 20%.
Achieve absolute performance with improved sensitivity
To reach lower limits of quantitation and meet regulatory requirements, even for challenging negative ionizing compounds, you need an instrument that delivers absolute performance. The Xevo TQ Absolute XR IVD Mass Spectrometer delivers up to 15x better sensitivity for challenging negative ionizing compounds than the previous product, so you can make confident decisions, faster.
Challenging complex separations, solved
With industry-leading separations performance, the ACQUITY UPLC I-Class PLUS System provides the most powerful solution to the most critical need in separation science today–successfully analyzing clinical compounds that are limited in amount or availability amid a complex matrix, more rapidly than ever before. Developed to produce the most accurate and reproducible separations, you’ll get the most detailed data possible and significantly accelerate your laboratory results.
Simplify workflows with intuitive informatics solutions
MassLynx (IVD) Mass Spectrometry Software with TargetLynx XS (IVD) Application Manager increases the speed at which you can convert your sample data into valuable knowledge. It provides you with the fundamental platform to acquire, analyze and manage data information in a clinical environment with features like:
- MassLynx Software Basic Security, which enhances user experience through simplified workflow while securing method files from accidental revision.
- The MassLynx Software Sample List intuitive user interface, which simplifies interactions with your Waters LC-MS/MS system with a single point to initiate all activities related to system control, sample information input, and data processing.
- TargetLynx Application Manager, which transforms LC-MS/MS data into usable and meaningful results for quantitative analysis and more for clinical analyses.
Maximum uptime, minimal maintenance
Redefine the way that you operate your instrument with the popular electrospray ionization (ESI) tool-free probe. Don’t worry about time-consuming optimization steps with any tools since even changing the probe assembly, including the capillary, is entirely tool-free. The robust Xevo Mass Spectrometer source design requires minimal maintenance without the need to vent the instrument resulting in maximum instrument uptime, ensuring you get the results you need the first time no matter who operates and maintains the instrument.
Realize absolute efficiency and lower operational costs
Many businesses are trying to actively address environmental sustainability while also reducing operational costs – and the Xevo TQ Absolute XR IVD Mass Spectrometer helps make that possible.
With an approximately 45% smaller footprint than leading competitors and about 50% lower electricity and gas consumption, the system helps reduce operational costs while supporting more sustainable lab operations.
Reduced heat output contributes to a more comfortable lab environment, and simplified maintenance helps maximize uptime. This product has been independently assessed using the My Green Lab® ACT® Ecolabel.
The ACT Ecolabel provides third party verified data on environmental impact across manufacturing, energy use, packaging, and end of life
Automated data workflow solutions
The MassLynx LIMS Interface conforms to the Health Level 7 (HL7) protocols and automates the exchange of information with a third-party LIMS provider, improving the data workflow while minimizing transcription errors. The MassLynx Tecan File Converter and direct connection with Hamilton automatic liquid handlers provides sample tracking from primary tube to result without any operator intervention, delivering secure data transfer and reducing transcription errors.
Your clinical laboratory, covered
Clinical diagnostics laboratories depend on reliable instrument performance, maximum uptime, and effective cost control. Routine maintenance and rapid support help keep time-sensitive, high-throughput testing running without interruption. Waters FlexCHOICE: mySystem Coverage is designed to support these needs through regular performance maintenance visits and guaranteed on-site response when remote technical support cannot resolve an issue.