• Application Note

Doxepin in Serum

Doxepin in Serum
  • Waters Corporation
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This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief demonstrates the analysis of doxepin in serum using Symmetry Columns. 

Introduction

The compounds analyzed in this study are:

  1. Butyl paraben (I.S.) 
  2. Doxepin 
Compounds

Experimental

HPLC Method

Column:

Symmetry Shield RP8, 3.9 x 150 mm, 5 µm

Guard Column:

Symmetry Guard Column, 3.9 x 20 mm, 5 µm

Part numbers:

Column - WAT200655, Guard - WAT200675

Mobile phase:

20 mM potassium phosphate, pH 7/methanol 38:62

Flow rate:

1.0 mL/min

Injection volume:

20 µL of reconstituted porcine serum extract

Temperature:

30 °C

Detection:

UV @ 254 nm

Results and Discussion

Featured Products

WA31763.79, June 2003

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