ACQUITY Premier System

ACQUITY Premier System

The next evolution in separation science is here

The next evolution in separation science is here

Maximizing the sensitivity, repeatability, and robustness of your LC and LC-MS applications is critical. The ACQUITY Premier System is the next evolution of the Performance LC System which include the ACQUITY UPLC H-Class PLUS and ACQUITY UPLC I-Class PLUS Systems. Along with the reliability, ruggedness, high quality, and configuration flexibility you expect from the ACQUITY UPLC PLUS Series, the ACQUITY Premier System delivers a step change in chromatographic performance, lab efficiency, and risk control.

The ACQUITY Premier System features MaxPeak High Performance Surfaces (HPS) Technology, which offers improvements in separation and detection of metal-sensitive analytes, enabling you to minimize the risk of undetected analytes – for increased efficiency and confidence in your results.

The ACQUITY Premier System reduces adsorption losses due to metal interactions. ACQUITY Premier System
The ACQUITY Premier System has received an ACT® label for its environmentally responsible design.

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Specifications

Maximum Operating Pressure

15,000 psi

pH Range

1 to 12.5

Operating Flow Rate Range

0.001 to 2.000 mL/min

Injection type

Flow-Through Needle, Fixed Loop

Sample Flow Path

Inert (MaxPeak HPS Technology)

Sample Carryover

≤0.002%

Sample Compartment

4 to 40 C

Pump Options

Binary, Quaternary

Solvent Conditioning

Active pre-heating as standard;

Column Tracking

eCord Technology column information management tracks and archives column usage

Column Capacity

Six columns up to 150 mm length, up to 4.6 mm internal diameter (I.D.)

Maximum Sample Capacity

8,064 (with Sample Organizer)

Detector Options

TUV Detector

PDA eλ Detector

FLR Detector

RI Detector

ELS Detector

Mass Spectrometers

External Control

Empower Software

MassLynx Software

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Physical Specifications

QSM or BSM, SM-FTN, CH-A

Width: 34.3 cm (13.5 in.)

Height: 71.1 cm (28.0 in.)

Depth: 71.2 cm (28.0 in.)

Overview

  • Minimize risk of undetected analytes with MaxPeak High Performance Surfaces (HPS) Technology
  • Decrease time-to-result and increase overall efficiency by eliminating time-consuming system and column passivation
  • Improve peak shape and reproducibility for the most challenging metal-sensitive compounds
  • Achieve high-precision injections with direct inject sampling
  • Reduce time on method development
  • Multi-software platform support options with Empower, MassLynx, and UNIFI
  • Achieve sample injection versatility, depending upon your application, with the flow-through needle and fixed loop injector options

Recommended Use: For improving the peak shape and reproducibility for the most challenging metal-sensitive compounds.


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Tough metal-sensitive compounds? Not anymore.

Non-specific adsorption of metal-sensitive compounds is an unpredictable challenge, leading to long system passivation times, chromatography with large RSDs, and broad peaks that can be a challenge to detect. The ACQUITY Premier System is built with proven ACQUITY technology, which offers true UPLC performance, ultra-low dispersion, and high resolution.

Designed with MaxPeak HPS Technology, the ACQUITY Premier System improves peak shape and reproducibility for the most challenging metal-sensitive compounds.


Boost method efficiency with UPLC technology

Take your methods to the next performance level by leveraging the benefits of Ultra Performance Liquid Chromatography (UPLC) technology to improve your existing HPLC methods. By scaling your methods to UPLC, your laboratory will benefit from the combination of increased resolution, sensitivity, and speed that comes with modern small-particle chemistries.

Along with fast UPLC analysis times, the ACQUITY Premier System reduces the need for system passivation to optimize assays for metal-sensitive compounds. Take your assays to the next level of efficiency, not only with faster analysis times, but also reduced system downtime, decreased reagent costs, and, ultimately, improved lab productivity.


Power up recovery and sensitivity

The ACQUITY Premier System minimizes metal-sensitive analyte loss, improving recovery and limits of detection. Couple the ACQUITY Premier System with a Waters mass spectrometer to confidently identify and quantify unknown compounds in complex samples and confirm trace components at the lowest possible levels.


Reproducible results with a reliable partner

The ACQUITY Premier System and ACQUITY Premier Columns are holistically designed to reduce analyte losses and improve repeatability for a diversity of metal-sensitive analytes that interact with metal surfaces in conventional LC technology. Waters also delivers world-renowned services and support, tailored to optimize your laboratory productivity while addressing budget realities. Our offerings help you maintain peak system performance, minimize downtime, address scientific application challenges, and support stringent compliance requirements. 


Certified for sustainable design

The ACQUITY Premier System has received an ACT® label certification for its environmentally responsible design and manufacturing. Produced in a renewable-powered, resource-efficient facility, the system incorporates 25–40% recycled content, responsible chemical management practices, and sustainable packaging to minimize its environmental footprint. Built for longevity and high performance, the ACQUITY Premier System supports laboratories in reducing waste and energy consumption while maintaining exceptional analytical quality. By combining sustainability with innovation, the ACQUITY Premier System reflects the ongoing commitment by Waters to advancing scientific excellence responsibly.

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Related

Confidently identify known and unknown compounds with Waters Mass Spectrometry Systems. We have MS instruments to suit various workflows and applications.

Experience the highest level of chromatographic performance, flexibility, and assurance while mitigating unwanted analyte/surface interactions with MaxPeak Premier Columns.
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