The Waters GTxResolve 2000 Å SEC column, MaxPeak Premier 3 µm is designed with low-adsorption MaxPeak hardware and advanced bridged ethylene HO-PEO particles. This innovative composition ensures high recovery for GTx drugs ranging from 800 to 2500 Å in diameter, including lipid nanoparticles (LNPs), plasmids, and viral vectors. Engineered for extended column lifetimes, minimal secondary interactions, and enhanced MALS sensitivity, this solution supports the development of multi-attribute platform methods. It enables comprehensive integrity and heterogeneity analyses of LNP formulations, plasmid topology assessments, and improved detection of ejected transgenes and aggregates in viral vector applications.
Chimie |
SEC |
Mode de séparation |
SEC |
Particules de support |
Silica |
pH Range Min |
2.5 pH |
pH Range Max |
8 pH |
Temperature Limits |
60 C |
Maximum Pressure |
2000 psi (140 Bar) |
Endcapped |
Non |
Technologie de greffage |
SEC |
Silanol Activity |
Low |
Particle Shape |
Spherical |
Granulométrie |
3 µm |
Endfitting Type |
Parker-style |
Taille des pores |
2000 Å |
Format |
Colonne Premier |
Superficie |
19 |
Système |
HPLC, UHPLC, UPLC |
Technologie de particules |
Silice |
Technique |
SEC |
Classification USP |
L33 |
Diamètre interne |
4.6 mm |
Longueur |
150 mm |
Carbon Load |
1.2 % |
UNSPSC |
41115709 |
Application |
Gene Therapeutics |
Gamme |
GTxResolve |
Type de produit |
Colonnes |
Units per Package |
1 pk |
eConnect |
No |