• Note d'application

Promethazine – Impurities Profile

Promethazine – Impurities Profile
  • Waters Corporation
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This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief highlights the impurities profile of Promethazine using SymmetryShield Columns.

Introduction

Promethazine HCL impurities are studied in this application brief.

Experimental

HPLC Method

Column:

SymmetryShield RP18, 3.0 x 150 mm, 5 μm (p/n: 186000692)

Mobile phase A:

20 mM potassium phosphate, pH 7.0

Mobile phase B:

Acetonitrile

Flow rate:

1.0 mL/min

Injection volume:

10 μL of 0.5 mg/mL

Detection:

UV @ 254 nm

Gradient

Results and Discussion

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WA31763.133, June 2003

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