Référence du produit : 186004032
MassPREP Micro Desalting Column

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Product Description

"The MassPREP on-line desalting column can effectively desalt proteins prior to LC-MS analyses. Because non-volatile salts (e.g., NaCl) cansuppress ionization of intact proteins leading to poor detection sensitivity, it is important to remove or significantly minimize the introduction ofthese compounds into the mass analyzer. The reversed-phase phenyl material contained in MassPREP on-line column successfully “traps” proteins,allowing the salts to be washed to waste prior to protein elution into the mass spectrometer. With an optimized LC-MS method, cycle times as lowas 4 minutes (for intact antibody) and 10 minutes (for reduced antibody) are achievable."

Specifications

  • Brand

    MassPREP

  • Product Type

    Columns

  • Units per Package

    1 pk

  • Carbon Load

    15 %

  • Bonding Technology

    Phenyl-Hexyl

  • Chemistry

    Phenyl

  • Endcapped

    Yes

  • Endfitting Type

    Direct-Connect

  • Format

    Direct Connect Column

  • Inner Diameter

    2.1 mm

  • Length

    5 mm

  • Separation Mode

    Reversed Phase

  • Molecular Weight Range Min

    1000

  • Molecular Weight Range Max

    15000

  • Particle Shape

    Spherical

  • Particle Size

    20 µm

  • Particle Substrate

    Polymethacrylate

  • Pore Size

    1000 Å

  • USP Classification

    L11

  • pH Range

    2 pH

  • pH Range

    12 pH

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