 
            
        This is an Application Brief and does not contain a detailed Experimental section.
This application brief highlights the scaling-up of beta-blockers.
Compounds used in this study:
1. Metoprolol (50 mg/mL)
2. Oxprenolol (25 mg/mL)
3. Propranolol (5 mg/mL)
 
            
        | Column: | SunFire C18 4.6 x 100 mm, 5 μm (p/n: 186002558) 19 x 100 mm, 5 μm (p/n: 186002567) | 
| Mobile phase A: | 0.1% HCOOH in Water | 
| Mobile phase B: | 0.1% HCOOH in ACN | 
| Temperature: | Ambient | 
| Detection: | UV @ 254 nm | 
| Instrument: | AutoPurification System | 
 
            
        WA41885, March 2005