Waters Fraction Collector IV
Precise, reliable fraction collection for diverse applications
Delivering precise, reliable fraction collection amid increasing sample complexity and molecular diversity is challenging.
The Waters Fraction Collector (WFC) IV is an easy to use, robust, and highly adaptable fraction collector that integrates seamlessly with Waters analytical and purification LC systems, enabling reliable fraction collection for various applications, including peptide and oligonucleotide purification.
Collect with confidence and precision using flexible time and peak based collection modes to accurately collect peaks of interest while directing unwanted peaks and solvent to waste for high purity and recovery fraction collection.
Designed for evolving needs, the WFC IV achieves 50% greater fraction capacity than the WFC III and supports a wide range of collection racks—from microtiter plates to preparative funnels.
Waters Fraction Collector IV
Specifications
|
Flow rate range |
0.5 mL/min to 300 mL/min |
|
Standard test tube |
12.0-18.0 mm O.D. rack, max. 162 |
|
Scintillation vial (17 mm O.D.) |
Max. 162 |
|
Scintillation vial (30 mm O.D.) |
Max. 60 |
|
Microtiter plate |
6×96 well plate |
|
Preparative funnel |
6×32-position rack |
|
Microcentrifuge tube rack |
Up to three racks, 162 positions |
|
Waters 3767 rack |
Max. 1 |
|
Methods |
Time- and peak-based (threshold/slope), and/or any combination of two of these. Manual collection. |
|
Nozzle travel time |
0.2 s (adjacent test tube movement time) |
|
Electrical characteristics |
AC 100 V – 240 V, 50 Hz/60 Hz |
|
Communication |
Ethernet communication |
|
External dimensions |
Width: 300 mm Depth: 600 mm Height: 544 mm Weight: 14.1 kg (body only) |
|
Temp. range |
4 to 40°C (39 to 104°F) |
|
Item |
Part Number |
|
Waters Fraction Collector IV |
176006325 |
|
Diverter Valve Options |
|
|
3-way Diverter Valve, Standard |
700015008 |
|
3-way Diverter Valve, Low-residual |
700015012 |
|
Rack Options |
|
|
Standard tube rack with holders |
700015009 |
|
Standard tube rack without holders |
700015013 |
|
Standard tube rack with 12 mm-dia. holders |
700015014 |
|
Microplate rack |
176006334 |
|
Vial rack plate, 17 mm O.D. |
176006336 |
|
Vial rack plate, 30 mm O.D. |
176006337 |
|
Microcentrifuge tube rack |
176006335 |
|
2 mL Vial Rack |
176006338 |
|
Waters 3767 rack plate |
700015021 |
|
SS Prep funnel rack |
700015022 |
|
Prep funnel rack 32 holes, three per package |
700015023 |
|
Tube support (12mm O.D., 30 ea/pk) |
725000153 |
|
General Ordering Items |
|
|
Drip tray drain tube & plug kit |
700002169 |
|
Drain |
700015011 |
Overview
- Seamless integration with Waters analytical and purification LC systems supports reliable fraction collection from analytical to preparative scales, with flow rates up to 300 mL/min.
- Precise fraction collection with flexible time- and peak-based modes, enabling accurate collection of peaks of interest, while a diverter valve directs unwanted peaks and extraneous solvent to waste to ensure high-purity, high-recovery results.
- Simplified operation with an integrated software interface, enabling intuitive use through Empower, MassLynx, or ChromScope Software.
- Designed for evolving needs, the WFC IV delivers 50% greater capacity than WFC III and supports a wide range of collection racks, from microtiter plates to preparative funnels.
Recommended Use: Easy to use, robust, and highly adaptable fraction collector for reliable fraction collection from analytical to preparative scales.
Reliable and highly adaptable fraction collector for analytical to preparative LC purification
Seamlessly integrate the WFC IV with Waters Analytical and Purification LC systems like the Waters ACQUITY UPLC Systems, Arc Systems, LC Prep 150 System, Modular System, and LC Prep AutoPurification System. The WFC IV supports reliable fraction collection for a wide range of applications, including natural products, synthetic compounds, peptide and oligonucleotide purification, from analytical through semi-preparative to preparative scales at flow rates up to 300 mL/min.
Collect exactly what you need
The WFC IV gives you full control over how, when, and where fractions are collected—so you can confidently collect only what you need.
Flexible collection modes, including time- and peak-based collection, can be triggered independently or combined to support advanced workflows, such as pooling of repeated runs into common vessels.
Automated peak detection and collection using detector input from the LC system enables precise collection of peaks of interest, while the diverter valve directs unwanted peaks and extraneous solvent to waste, increasing target fraction purity, improving collection efficiency, and maximizing overall preparative productivity.
Simplified fraction collection with more capacity
The WFC IV is easy to use, with an integrated software interface that supports seamless operation through Empower, MassLynx, or ChromScope Software. Customizable collection bed layouts, flexible rack configurations, and real time monitoring of collection location and system status provide greater control and confidence, enabling accurate, efficient, and adaptable fraction collection as your workflows evolve.
Delivering better performance with 50% greater fraction capacity than WFC III, the WFC IV accommodates multiple collection vessel types, including standard test tubes, microcentrifuge tubes, scintillation vials, microtiter plates, preparative funnels, and more. This flexibility enables easy scaling from analytical to preparative purification.
Resources
Documents
What do you want to do?
