• Note d'application

Atorvastatin - XTerra Phenyl

Atorvastatin - XTerra Phenyl
  • Waters Corporation
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Atorvastatin cholesterol lowering drug chemical structure

This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief demonstrates the analysis of atrovastatin using XTerra Columns. 

Introduction

In this study the compound analyzed is atorvastatin.  

Atorvastatin

Experimental

Conditions

Column:

XTerra Phenyl, 4.6 x 100 mm, 3.5 µm

Part number:

186001139

Mobile phase A:

10 mM NH4COOH, pH 3.0

Mobile phase A:

10 mM NH4HCO3, pH 7.0

Mobile phase A:

10 mM NH4HCO3, pH 10.0

Mobile phase B:

ACN

Isocratic Conditions as Indicated

Flow rate:

1.4 mL/min

Injection volume:

2 µL

Sample Concentration:

0.25 mg/mL

Temperature:

30 °C

Detection:

UV @ 254 nm

Instrument:

Alliance 2695, 2996 PDA

Mobile Phase pH

USP Tailing

3.0

0.95

7.0

1.11

10.0

1.06

Results and Discussion

Atorvastatin

Featured Products

WA20738.015, June 2002

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