186010733

SKU: 186011345
GTxResolve 2000 Å SEC Column, MaxPeak Premier 3 μm, 4.6x30 mm Guard Cartridge 1/pk (for use with both 4.6 and 7.8 mm ID analytical columns)


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Product Description

The Waters GTxResolve 2000 Å SEC column, MaxPeak Premier 3 µm is designed with low-adsorption MaxPeak hardware and advanced bridged ethylene HO-PEO particles. This innovative composition ensures high recovery for GTx drugs ranging from 800 to 2500 Å in diameter, including lipid nanoparticles (LNPs), plasmids, and viral vectors. Engineered for extended column lifetimes, minimal secondary interactions, and enhanced MALS sensitivity, this solution supports the development of multi-attribute platform methods. It enables comprehensive integrity and heterogeneity analyses of LNP formulations, plasmid topology assessments, and improved detection of ejected transgenes and aggregates in viral vector applications.

Specifications

  • Chemistry

    SEC

  • Separation Mode

    SEC

  • Particle Substrate

    Silica

  • pH Range Min

    2.5 pH

  • pH Range Max

    8 pH

  • Temperature Limits

    60 C

  • Maximum Pressure

    2000 psi (140 Bar)

  • Endcapped

    No

  • Bonding Technology

    SEC

  • Silanol Activity

    Low

  • Particle Shape

    Spherical

  • Particle Size

    3 µm

  • Endfitting Type

    Parker-style

  • Pore Size

    2000 Å

  • Format

    Premier Column

  • Surface Area

    19

  • System

    HPLC, UHPLC, UPLC

  • Particle Technology

    Silica

  • Technique

    SEC

  • USP Classification

    L33

  • Inner Diameter

    4.6 mm

  • Length

    30 mm

  • Carbon Load

    1.2 %

  • UNSPSC

    41115709

  • Application

    Gene Therapeutics

  • Brand

    GTxResolve

  • Product Type

    Guards

  • Units per Package

    1 pk

Product Support

Documents

Documents



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