BioResolve Premier Columns
Fast, reproducible results for PAT, bioprocessing, drug discovery, and drug development applications
With BioResolve Premier Columns, your lab can achieve fast analysis of large biomolecules, like monoclonal antibodies (mAbs) and multi-specifics (msAbs), with columns that are ideal for rapid identification of clones, faster analysis, and real-time insights of mAb and msAb critical quality attributes.
Ideal for drug discovery and mass spectrometry labs, BioResolve Premier Columns are available in short and ultra short, high-throughput configurations for faster chromatography that meet your lab’s unique requirements.
BioResolve Premier Columns
Waters BioResolve Protein A Affinity columns, designed to provide greater analytical sensitivity to enable fast, accurate decision-making.
Specifications
Overview
- Quickly analyze large biomolecules, including monoclonal antibodies (mAbs), multi-specifics (msAbs), and other advanced antibody therapeutics
- Integrate fast, reproducible column technology into the workflow for efficient reversed phase, ion exchange, and affinity-based protein analysis
- Reduce unwanted analyte/surface interactions with MaxPeak High Performance Surfaces
- Choose from high-throughput configurations for faster chromatography in PAT, upstream and downstream bioprocessing
Recommended Use: For faster affinity, reversed-phase (RP) and ion exchange (IEX) chromatography where high throughput is desired, including PAT, upstream and downstream bioprocessing, drug discovery and mass spectrometry labs.
BioResolve Premier Column Featured Technologies
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Reduce analyte/surface interactions -
Increase analyte recovery
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Better peak shape
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Increase sensitivity
BioResolve Premier Column Characteristics
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Enhanced peak shape for easier analysis
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Greater sensitivity for mAbs, multi-specifics, and conjugates
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Faster decision-making and better process control
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Reliable reproducibility injection-to-injection and batch-to-batch
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Simplified 2D applications (e.g., ProA-SEC) on all LC systems including UPLC
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High-pressure tolerance for efficient quality attribute assessment
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Improved peak capacity for better component resolution
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Minimal injection-to-injection carryover for increased confidence of analyses
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Ability to operate at lower temperatures for less on-column sample degradation
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Ensured column-to-column performance by being quality control (QC) tested with a NIST-based, mAb subunit standard
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LC system (HPLC, UHPLC, UPLC) agnostic, doesn’t compromise required separation performance
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Ability to reliably separate, with accurate charge variant quantitation, a wide range of mAbs using optical or LC-MS compatible mobile phases
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Excellent batch-to-batch and column-to-column performance consistency
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LC system (HPLC, UHPLC, UPLC) agnostic, doesn’t compromise required separation performance
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Ensured column-to-column performance by being QC tested with a NIST-based, mAb Charge Variant standard
Faster chromatography for high-throughput applications
BioResolve Premier Columns deliver fast analysis for large biomolecules, including monoclonal antibodies (mAbs), and are ideal for the rapid identification of clones and faster analysis for real-time insights of mAb critical quality attributes. Available in reversed phase (RP) and strong cation exchange (SCX) chemistries for high throughput applications, your lab can achieve fast chromatography with excellent performance.
See and do more by reducing analyte/surface interactions
MaxPeak Premier High Performance Surfaces (HPS) Technology takes the sensitivity of BioResolve Premier Columns to the next level. See and do more by reducing analyte/surface interactions for more reproducible results. With MaxPeak Premier HPS, you increase analyte recovery and obtain a better peak shape for greater confidence in your results.
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