This is an Application Brief and does not contain a detailed Experimental section.
This application brief demonstrates analysis of trazodone.
The compounds used in this study are –
| 
                     Compounds  | 
                     USP Tailing Factors  | 
            
|---|---|
| 
                     1-(3-chlorophenyl)peperazine  | 
                     1.31  | 
            
| 
                     Maprotiline (I.S.)  | 
                     1.21  | 
            
| 
                     Trazodone  | 
                     1.12  | 
            
            
        | 
                     Column:  | 
                     Symmetry Shield RP8, 3.9 x 150 mm, 5 μm  | 
            
| 
                     Part numbers:  | 
                     WAT200655  | 
            
| 
                     Mobile phase:  | 
                     50 mM phosphate, pH7.0/methanol 36:64  | 
            
| 
                     Flow rate:  | 
                     1.0 mL/min  | 
            
| 
                     Injection volume:  | 
                     25 μL  | 
            
| 
                     Detection:  | 
                     UV @ 250 nm  | 
            
            
        WA31763.171, June 2003