 
            
        This is an Application Brief and does not contain a detailed Experimental section.
This application brief highlights the analysis of Terfenadine using SymmetryShield Columns.
Terfenadine structure is shown below.
 
            
        | Column: | SymmetryShield RP18, 4.6 x 150 mm, 5 μm (p/n:186000109) | 
| Mobile phase: | 20 mM phosphate buffer, pH 7.0/acetonitrile 25:75 | 
| Flow rate: | 1.0 mL/min | 
| Injection volume: | 5 μL | 
| Detection: | UV @ 220 nm | 
1. 1.04
 
            
        WA31763.164, June 2003