 
            
        This is an Application Brief and does not contain a detailed Experimental section.
This application brief highlights the impurities profile of Promethazine using SymmetryShield Columns.
Promethazine HCL impurities are studied in this application brief.
 
            
        | Column: | SymmetryShield RP18, 3.0 x 150 mm, 5 μm (p/n: 186000692) | 
| Mobile phase A: | 20 mM potassium phosphate, pH 7.0 | 
| Mobile phase B: | Acetonitrile | 
| Flow rate: | 1.0 mL/min | 
| Injection volume: | 10 μL of 0.5 mg/mL | 
| Detection: | UV @ 254 nm | 
 
            
         
            
        WA31763.133, June 2003