• Application Note

Profens (Isocratic) - 4.6 x 20 mm Intelligent Speed Separation

Profens (Isocratic) - 4.6 x 20 mm Intelligent Speed Separation
  • Waters Corporation
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Factory production of pills

This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief highlights the separation of profens using Symmetry Intelligent Speed Columns.

Introduction

Compounds used in this application brief are:

1. Ketoprofen

2. Fenoprofen

3. Flurbiprofen

4. Ibuprofen

Experimental

HPLC Method

Column:

Symmetry C18, 4.6 x 20 mm, 3.5 μm IS (p/n: 186002090)

Guard Column:

SymmetryShield RP18, 4.6 x 20 mm, 3.5 μm IS (p/n: 186002092)

Mobile phase A:

0.1% HCOOH in Water

Mobile phase B:

0.1% HCOOH in ACN

Isocratic:

65% A, 35% B

Flow rate:

3.0 mL/min

Injection volume:

10 μL

Temperature:

30° C

Detection:

UV @ 220 nm

Results and Discussion

Featured Products

WA31763.132, June 2003

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