• Application Note

Propranolol in Rat Plasma

Propranolol in Rat Plasma
  • Waters Corporation
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Blood plasma tube held in gloved hand

This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief highlights the analysis of propranolol in Rat plasma using XTerra C18 columns.

Introduction

Propranolol in rat plasma has been analyzed in this application brief.

Experimental

Conditions

Column:

XTerra MS C18 2.1 x 30 mm, 3.5 μm (p/n: 186000398)

Mobile phase A:

1.0% NH4OH

Mobile phase B:

ACN

Isocratic mobile phase composition:

50% A; 50% B

Flow rate:

0.2 mL/min

Injection volume:

50 mL

Detection:

MS ESI+

Instrument:

Alliance 2790, Micromass Quattro Ultima

Ion source:

ESI+

Source temp.:

150°C

Gas cell:

1.5e-3 mbar, 25 eV

Desolvation temp.:

350 °C

Cone gas flow:

150 L/hr

Drying gas flow:

600 L/hr

Cone voltage:

20 V

Results and Discussion

Featured Products

WA20738.092, June 2002

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