MaxPeak Premier Solutions

With the introduction of MaxPeak High Performance Surfaces (HPS) Technology, Waters has redefined what's possible in liquid chromatography—reducing variability, improving analyte recovery, and eliminating the need for time-consuming passivation procedures.

With the introduction of MaxPeak High Performance Surfaces (HPS) Technology, Waters has redefined what's possible in liquid chromatography—reducing variability, improving analyte recovery, and eliminating the need for time-consuming passivation procedures.

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ACQUITY Premier System in lab with scientist opening door

Overview

Quantifiable advancements in liquid chromatography

MaxPeak Premier Solutions represent a significant leap forward in chromatographic performance. By integrating MaxPeak High Performance Surfaces (HPS) Technology, Waters has effectively addressed challenges associated with metal-sensitive analytes—reducing variability, enhancing analyte recovery, and eliminating the need for system or column conditioning.

Enhance analyte recovery: In acidic peptides analysis, ACQUITY Premier System featuring MaxPeak HPS Technology demonstrated a 4x increase in peak area and a 34x increase in MS detector response.*
Improve sensitivity and dynamic range: ACQUITY Premier System and Column yielded a 12.5x increase in signal intensity and a 10x improvement in detection limits for oligo analysis. *
Reduce variability: Retention time reproducibility across 3 systems and 9 LC separation conditions showed RSDs of <1 second for most peptides, ensuring reliable results.
Improve peak shape and reduce metabolomic analyte adsorption: When analyzing TCA cycle metabolites in human urine, MaxPeak Premier Columns provided improved peak symmetry and reduced tailing for acidic compounds like citric and isocitric acid—for greater reproducibility and sensitivity.
Eliminate conditioning or passivation steps: MaxPeak HPS Technology into system and column hardware effectively eliminates the need for time-consuming conditioning/passivation procedures, increasing lab efficiency.

These quantifiable enhancements underscore the transformative impact of MaxPeak Premier Solutions in liquid chromatography, offering researchers and analysts a robust and reliable platform for high-performance separations.

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* As compared to conventional systems and columns.

Why Choose MaxPeak Premier Solutions?

Sharper Peaks, Higher Recovery
Achieve better signal-to-noise ratios and cleaner separations.

Unmatched Reproducibility
Minimize run-to-run and batch-to-batch variability.

Streamlined Method Development
Spend less time troubleshooting and more time analyzing.

Regulatory Confidence
Trusted by leading labs operating in GxP and regulated environments.

Technology That Powers Results

Waters MaxPeak Premier Solutions deliver true end-to-end separations coverage—from early discovery through development to regulated manufacturing.



	Discovery Characterization	Development	Manufacturing QC
ACQUITY Premier System	ACQUITY Premier System	ACQUITY Premier System	ACQUITY Premier System
ACQUITY Premier System
Arc Premier System	Arc Premier System	Arc Premier System	Arc Premier System
Arc Premier System
Alliance iS Bio HPLC System	Alliance iS Bio HPLC System	Alliance iS Bio HPLC System	Alliance iS Bio HPLC System
Alliance iS Bio HPLC System
QuanRecovery Vials and Plates	QuanRecovery Vials and Plates	QuanRecovery Vials and Plates	QuanRecovery Vials and Plates
QuanRecovery Vials and Plates
MaxPeak Premier Columns	MaxPeak Premier Columns	MaxPeak Premier Columns	MaxPeak Premier Columns
MaxPeak Premier Columns

Whether you’re working in non-regulated environments or GxP-compliant labs, Waters provides seamless, surface-optimized LC technology for every stage of your biopharma workflow. Couple the ACQUITY Premier System with a Waters mass spectrometer to confidently identify and quantify unknown compounds in complex samples and confirm trace components at the lowest possible levels.

To the Max - Eliminate Doubt with MaxPeak Premier Columns

When selecting an analytical column for your method, uncontrolled interactions between your analytes and the column hardware can cause variability, casting doubt on results accuracy. Waters MaxPeak Premier Columns help eliminate ambiguity, estimation, and doubt – to maximize accuracy, control, speed, reproducibility, and confidence in results.

Learn more about Waters MaxPeak Premier Columns.

When selecting an analytical column for your method, uncontrolled interactions between your analytes and the column hardware can cause variability, casting doubt on results accuracy. Waters MaxPeak Premier Columns help eliminate ambiguity, estimation, and doubt – to maximize accuracy, control, speed, reproducibility, and confidence in results.

Learn more about Waters MaxPeak Premier Columns.

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MaxPeak Premier Columns Website Homepage Innovations

Solutions

Waters MaxPeak Premier Systems improve separation and detection of metal-sensitive analytes - so you can see more of your sample.

Waters MaxPeak Premier Systems improve separation and detection of metal-sensitive analytes - so you can see more of your sample.

See everything in your sample

ACQUITY Premier System

Ideal for early-stage discovery and characterization with uncompromised sensitivity.

See clearly and consistently, with confidence

Arc Premier System

A robust development platform offering method scalability and easy transition from HPLC.

Intuitive simplicity for biopharma

Alliance iS Bio HPLC System

Purpose-built for regulated biopharma manufacturing, with bio-inert technology to maintain data integrity in GxP workflows.

BioAccord LC-MS System with ACQUITY Premier BSM SM CH-A TUV with bottles on top and a monitor to the right

Confidence in routine biopharma workflows starts here

BioAccord System

LC-MS platform with built-in compliance tools, perfect for process monitoring and release testing.

Together with MaxPeak Premier Columns, QuanRecovery Vials, and inert columns, these systems form an integrated suite that reduces variability and simplifies workflows across your entire product lifecycle.

Quality consumables to minimize metal-sensitive analyte interactions

Quality consumables to minimize metal-sensitive analyte interactions

ACQUITY and XBridge Premier Protein SEC 250A Columns combine MaxPeak Premier and BEH-PEO Technologies for reliable SEC data.

See all of your sample with MaxPeak Premier Columns

MaxPeak Premier Columns

MaxPeak Premier Columns, feature MaxPeak High Performance Surfaces (HPS) Technology, to create the most universal column platform for chromatographers who need to reduce variability risks and save time, all while increasing recovery and sensitivity.

FlexCHOICE: mySystem Coverage Solutions for clinical laboratories.

Productivity up. Costs? Way down

FlexCHOICE Instrument Service Coverage

Safeguard against lost productivity, maintain system peak performance, and protect your lab against unexpected downtime from unplanned outages with our three coverage options for your unique lab requirements.

With Waters LC systems, you will achieve the quality separations you need for your business.

Make science more accessible with Waters Capital

Payment Solutions

Maximize your lab’s financial resources and minimize risk with innovative financing solutions, including leasing, rental, and technology refresh, from Waters Capital.

The data speaks for itself

Overlay chromatogram of the NSAIDs Mix for three different column lots; Lot A (Black), Lot B (Red), and Lot C (Blue).

Analysis of Dexamethasone Sodium Phosphate. Improved peak area and peak shape using the ACQUITY Premier Solution.

Comparison of chromatographic performance for stressed control sample preparations analyzed with three system set-ups: (1) ACQUITY Arc System/XBridge XP Column, (2) ACQUITY Arc System/XBridge Premier Column, and (3) Arc Premier System/XBridge Premier Column. Inset shows recovery of the low-level degradation product identified as Tenofovir.

Aggregate and Fragment analysis of Renflexis between ACQUITY Premier System and Arc Premier System.

SEC separation of a USP mAb System Suitability Solution on a legacy HPLC system and the Alliance iS Bio HPLC System with a BioSuite Diol SEC column

A) SEC separation of a USP mAb System Suitability Solution on a legacy HPLC system and the Alliance iS Bio HPLC System with a BioSuite Diol SEC column. B) System suitability results for n=7 injections on both instruments. C) Bar plot comparison of the LMWS recovery on both systems.

Webinars and Resources

Improving Chromatographic Separations Of Biopharmaceuticals With MaxPeak High Performance Surfaces (HPS) Technology

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Explore Waters HPLC, UPLC, UHPLC, Purification, and Specialty chromatography systems, ideal for liquid chromatography (LC), LC-MS, GPC, SFC, and SEC analysis.

Columns

Meet all your application, methods development, validation, and transfer needs throughout your organization with Waters HPLC, UPLC, UHPLC, GPC, SFC, and SEC columns.