Improving Quantitative Analysis of Red Wine Using the Xevo G2-XS QTof with SONAR Data Independent Acquisition (DIA)

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Lauren Mullin, Yunpeng Zhen, and Rob Plumb
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Application Notes
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Technical Notes
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In this technical note we describe the use of a novel data independent acquisition (DIA) mode known as SONAR for generation of highly selective HRMS spectra on Waters Xevo G2-XS QTof.

Technology benefits include:

  • Provides flexible targeted and non-targeted analysis of phenolic compounds of interest in red wine.
  • Improved MS/MS spectral clarity afforded by SONAR without the need for method development or prior knowledge of the sample.
  • Provides data for quantitation and identification in a single injection.

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