Introduction to High Resolution Mass Spectrometry
High resolution mass spectrometry (HRMS) is an important instrumental tool in the analytical laboratory, regardless of the application. Use of HRMS is imperative in the identification of unknown compounds. Unlike obtaining nominal mass (low-resolution) information by single or tandem quadrupole MS, HRMS allows for greater precision with mass measurements. By using exact mass, very small differences in mass can be observed which allows for differentiation between two (or more) compounds that a low-resolution MS would show as identical. Having exact mass data is expected for structural elucidation of unknowns; additionally, by using library screening for spectra obtained via HRMS, the identification of compounds can be simplified. We will introduce the fundamentals of HRMS, and explore several applications using HRMS in fields such as biopharmaceuticals, extractables and leachables, -omics, and environmental science.
Join us for this free half day seminar!
For additional information or questions please contact John_R_Simms@waters.com.
February 22, 2018
Carmel Tech Center
12368 Hancock Street
Carmel, IN 46032