The use of LC and LC/MS techniques to separate and characterize complex biological compounds is increasing. The use of one-and two-dimensional chromatography prior to mass analysis (i.e. “on-line” ion-exchange followed by gradient reversed-phase separations) is a promising adjunct to two-dimensional PAGE for separating difficult samples. To assist in these areas of investigation, Waters offers 1- and 2-dimensional LC/MS kits.
Waters nanoACQUITY UPLC 2D Kit provides high efficiency on-line 2D-LC/MS analysis for complex proteomics samples, such as protein global digests.