Literature


Results for mse
Description
Aiding Lithium Ion Secondary Battery Electrolyte Design via UPLC-MS and APGC-MS Analysis on a Single...
Library Number: APNT135046910 | Format: PDF | File Size: 1288.06 kB | Year: 2020 | Content Type: Application Notes

A protocol for determining the effect of lithium ion battery charge-discharge cycles on the composition of secondary battery electrolyte solutions and additives.

Employing UPLC-UV-ToF MSE and the UNIFI Scientific Information System for the Analysis of the Forced...
Library Number: APNT134923220 | Format: PDF | File Size: 1936.41 kB | Year: 2017 | Content Type: Application Notes

In this application note impurity identification of glipizide is characterized using UNIFI scientific information system platform.

Screening for Classical and Novel Drugs in Pooled Urine Using UPLC-Tof-MSE
Library Number: APNT134733981 | Format: PDF | File Size: 2250.05 kB | Year: 2013 | Content Type: Application Notes

This study presents the results of screening using a method based on UPLC in combination with Tof-MSE. The use of UPLC-Tof-MSE offers unique benefits for drug screening applications due to the acquisition of an unrestricted dataset with excellent sensitiv...

Identification of Non-Intentionally Added Substances (NIAS) in Food Contact Materials Using APGC-Xev...
Library Number: APNT134965919 | Format: PDF | File Size: 909.91 kB | Year: 2018 | Content Type: Application Notes

This application note describes a reliable GC-MS method for screening and structural elucidation of non-intentionally added substances (NIAS) in food packaging materials.

A Novel Approach Using UPLC-Tof MSE and the UNIFI Scientific Information System to Facilitate Impuri...
Library Number: APNT134884101 | Format: PDF | File Size: 2157.06 kB | Year: 2016 | Content Type: Application Notes

This application note describes comprehensive analysis of impurities using UNIFI Scientific Information System.

An Untargeted Exposure Study of Small Isolated Populations Using Atmospheric Gas Chromatography Coup...
Library Number: APNT134965044 | Format: PDF | File Size: 1414.95 kB | Year: 2018 | Content Type: Application Notes

Exposure studies involve complex data and subtle comparisons within the data sets. By utilizing the soft ionization of APGC and acquiring accurate mass data on both precursor and fragment ions in one method, a complete dataset can be produced.

Characterizing Low Abundance Monoclonal Antibody PTMs Using UNIFI Scientific Information System Pept...
Library Number: APNT134961689 | Format: PDF | File Size: 506.3 kB | Year: 2017 | Content Type: Application Notes

This application not describes peptide PTM analysis using UNIFI with Vion IMS QTof MS system.

The Utility of MSe for Toxicological Screening
Library Number: APNT10181650 | Format: PDF | File Size: 1426.6 kB | Year: 2010 | Content Type: Application Notes

To investigate the utility of the innovative data acquisition mode UPLC/MSe for the screening of toxicants in human urine.

Screening for a Panel of 12 Toxicologically-Relevant Drugs in Urine using Tof-MRM
Library Number: APNT134933921 | Format: PDF | File Size: 818.25 kB | Year: 2017 | Content Type: Application Notes

Here we present the analysis of common drugs in urine using Tof-MRM.

Determination of Aqueous Film Forming Foam (AFFF) Composition Using a Multivariate Analysis Approach...
Library Number: APNT134923199 | Format: PDF | File Size: 962.8 kB | Year: 2017 | Content Type: Application Notes

Aqueous film-forming foam (AFFF) mixtures were analyzed using Xevo G2-XS QTof in order to obtain full spectral accurate mass data from which a multivariate analysis (MVA) approach could be taken to identify unique components within the mixtures.

Automated Disulfide Bond Mapping in Comparing Innovator and Biosimilar mAbs Using UNIFI Software
Library Number: APNT134892431 | Format: PDF | File Size: 1703.89 kB | Year: 2016 | Content Type: Application Notes

This application note describes a UPLC-MSE analysis of monoclonal antibody (mAb) disulfide bond mapping.

Simultaneous in vivo Quantification and Metabolite Identification of Plasma Samples Using High Resol...
Library Number: APNT134742818 | Format: PDF | File Size: 2014.8 kB | Year: 2013 | Content Type: Application Notes

This application note summarizes the collaboration between Vertex and Waters to test and demonstrate a quan/qual workflow to determine robustness and reliability of QTof measurements, and compare them against the gold-standard tandem quadrupole workflows.

Characterization of Protein Impurities by Peptide Mapping with UPLC/MSE
Library Number: APNT10107766 | Format: PDF | File Size: 1643.65 kB | Year: 2009 | Content Type: Application Notes

This application note demonstrates the advantages of a UPLC/MSE method for characterization of protein digests. UPLC/MSE is a powerful tool that provides solutions for protein characterization challenges that are difficult to address with traditional pept...

Quantitation of High Resolution MS Data Using UNIFI: Acquiring and Processing Full Scan or Tof-MRM (...
Library Number: APNT134885232 | Format: PDF | File Size: 1557.49 kB | Year: 2016 | Content Type: Application Notes

This application note enables the user to collect HRMS data for quantitation, set up a simple quantitative processing method, and review the results within UNIFI.

Automated Quantitative Analysis of Antibody Drug Conjugates Using an Accurate Mass Screening Workflo...
Library Number: APNT134884059 | Format: PDF | File Size: 1452.77 kB | Year: 2016 | Content Type: Application Notes

This application note provides the Accurate Mass Screening workflow to streamline and facilitate the challenging quantitative analysis of antibody drug conjugate (ADC) peptides.

Metabolic Phenotyping Using Atmospheric Pressure Gas Chromatography-MS
Library Number: APNT134832772 | Format: PDF | File Size: 3853.34 kB | Year: 2015 | Content Type: Application Notes

This application note reports an APGC-TOF MSE profiling approach and its application to metabolic fingerprinting of Arabidopsis.

Qualitative Pesticide Screening and Binary Comparison of a Spinach Sample Using HRMS
Library Number: APNT134878186 | Format: PDF | File Size: 2094.28 kB | Year: 2016 | Content Type: Application Notes

In this application note, we describe the review of complex high resolution, non-targeted High Definition Mass Spectrometry data sets using workflows, filters, and views within an integrated scientific information system.

Metabolomics of Broccoli Sprouts Using UPLC with Ion Mobility Enabled LC/MSE and TransOmics Informat...
Library Number: APNT134744897 | Format: PDF | File Size: 4728.56 kB | Year: 2013 | Content Type: Application Notes

The aim of this work is to study how the complete set of small-molecule metabolites, the “metabolome,” of broccoli sprouts is modulated under different growth conditions.

Analysis of Deamidation and Oxidation in Monoclonal Antibody using Peptide Mapping with UPLC/MSE
Library Number: APNT10099045 | Format: PDF | File Size: 1932.5 kB | Year: 2009 | Content Type: Application Notes

Peptide mapping with UPLC/MSE improves the analytical efficiency of peptide characterization.

Identification and Quantification of Protein Modifications by Peptide Mapping with UPLC/MSE
Library Number: APNT10107770 | Format: PDF | File Size: 1798.22 kB | Year: 2009 | Content Type: Application Notes

In this application note, we demonstrate the utility of UPLC/MSE for identification and quantification of covalent modifications in a yeast alcohol dehydrogenase (ADH) digest.

High Sequence Coverage Peptide Mapping of a Monoclonal Antibody with UPLC/MSE
Library Number: APNT10099389 | Format: PDF | File Size: 1697.04 kB | Year: 2009 | Content Type: Application Notes

This application note demonstrates the high sequence coverage for both heavy and light chains in the analysis of a monoclonal antibody by UPLC/MSE.

Improving Peptide Mapping Productivity with UPLC/MSE and BiopharmaLynx: Comprehensive Protein Charac...
Library Number: APNT10128436 | Format: PDF | File Size: 2360.66 kB | Year: 2009 | Content Type: Application Notes

In this application note, we show how BiopharmaLynx software quickly automates assignment of peptide sequence information from MSE fragmentation data, even for cases of coeluting peptides.

Analysis of Plant Alkaloids through Accurate Mass Screening and Discovery
Library Number: APNT134856070 | Format: PDF | File Size: 2689.92 kB | Year: 2015 | Content Type: Application Notes

In this application note, the Forensic Toxicology Application Screening Solution with UNIFI1 was applied to a selection of plant alkaloids.

A Workflow Approach for the Identification and Structural Elucidation of Impurities of Quetiapine He...
Library Number: APNT10131073 | Format: PDF | File Size: 1864.54 kB | Year: 2015 | Content Type: Application Notes

We explore a multidisciplinary approach to impurity analysis using a systematic workflow that is capable of highly specific and highly sensitive detection and determination of impurities that are present in quetiapine hemifumarate active pharmaceutical in...

Qualitative Pesticide Screening of a Dried Cherry Sample Using HRMS
Library Number: APNT134853468 | Format: PDF | File Size: 2116.65 kB | Year: 2015 | Content Type: Application Notes

In this application note we demonstrate how a user can get from injection of a sample to submission of an accurate report using the workflows, views, and filters in UNIFI for multi-analyte screening in food and environmental samples.