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Matrix assisted laser desorption ionisation ion mobility separation mass spectrometry imaging of ex-...
Library Number: JOUR134792446 | Format: Web Page | File Size: - | Year: 2013 | Content Type: Journal Citations

In this article we talk about IMS-MS MALDI imaging acquisition at 150 and 30 µm spatial resolution

Analysis of siRNA Duplexes at Non-Denaturing UPLC Conditions Using MaxPeak Premier Column Technology
Library Number: APNT135088510 | Format: PDF | File Size: 441.72 kB | Year: 2021 | Content Type: Application Notes

This application note describes the analysis of formulation comprising of two siRNA duplexes.

Analysis of siRNA Drugs at Denaturing UPLC Conditions Using MaxPeak Premier Column Technology
Library Number: APNT135088513 | Format: PDF | File Size: 720.21 kB | Year: 2021 | Content Type: Application Notes

This application note demonstrates the utility of ACQUITY Premier Peptide BEH C18, 300 Å Column for analysis of small interfering RNA (siRNA) therapeutic candidate compound.

Arc HPLC System Instrument Specifications
Library Number: LITR135066607 | Format: PDF | File Size: 99.21 kB | Year: 2021 | Content Type: Literature

This document describes detailed specification about Arc HPLC System.

Advanced Therapeutic Medicinal Products: Adeno-associated Virus (AAV)
Library Number: LITR135088471 | Format: PDF | File Size: 3371.02 kB | Year: 2021 | Content Type: Literature

Table of Contents: Regulatory Situation (2021) Workflow Map Discovery Capsid Development Transgene Development Bioprocess CMS Product Specification Viral Vectors Common Analytical Technologies References and Further Reading

Analysis of Oligonucleotide Impurities on the BioAccord System with ACQUITY Premier
Library Number: APNT135087944 | Format: PDF | File Size: 1266.35 kB | Year: 2021 | Content Type: Application Notes

This application note demonstrates an automated, compliance-ready LC-MS workflow for purity analysis and intact mass confirmation of extensively modified oligonucleotides and their impurities.

Selecting a Liquid Chromatography Solution
Library Number: LITR135088178 | Format: PDF | File Size: 3736.44 kB | Year: 2021 | Content Type: Literature

A useful guide outlining various factors to consider when selecting your next liquid chromatography solution for the analysis of sugars and sugar substitutes.

OMNI Lab NBS Brochure
Library Number: LITR135088397 | Format: PDF | File Size: 663.97 kB | Year: 2021 | Content Type: Literature

This brochure describes about OMNI-LAB NBS which is a leading information management system for newborn screening laboratories.

OMNI Lab Newborn Screening Brochure
Library Number: LITR135088402 | Format: PDF | File Size: 572.96 kB | Year: 2021 | Content Type: Literature

This Brochure describes about OMNI-Lab NBS which allows Senior Medical/Scientific personnel to maximize time and resources in their laboratories while ensuring that NBS results generated through OMNI-Lab NBS are consistent and comprehensive.

MaxPeak Premier Columns for Small Molecule Analysis - Infographic
Library Number: MRKT135074459 | Format: PDF | File Size: 3511.66 kB | Year: 2021 | Content Type: Marketing/Online Tools

This infographic details about MaxPeak Premier Columns for small molecule analysis.

Waters Chromatography Portfolio Brochure
Library Number: LITR135088333 | Format: PDF | File Size: 12378.45 kB | Year: 2021 | Content Type: Literature

Waters has a complete portfolio of liquid chromatography and LC-MS solutions to provide you with accurate data to answer your lab's most pressing questions.

Separation and Detection of an Azido Impurity in Sartan Drug Substances Using the XSelect CSH Phenyl...
Library Number: APNT135088337 | Format: PDF | File Size: 396.57 kB | Year: 2021 | Content Type: Application Notes

This application note demonstrates UHPLC method with dual UV-MS detection for the quick and accurate, 3-minute analysis of this azido impurity, 5-[4’-(azidomethyl0[1,1’-biphenyl]-2-yl)-1H-tetrazole, and the sartan APIs irbesartan, lorsartan, and valsartan...

Comprehensive APC 2D Analysis of an Eight Component Polymer Blend
Library Number: APNT135088349 | Format: PDF | File Size: 395.15 kB | Year: 2021 | Content Type: Application Notes

Separation of a blend consisting of eight components that either have a similar or same chemistry or molecular weight might not be achievable with a single technique. Co-elution of some kind is a common cause when dealing with incomplete separation. The c...

Lipid Nanoparticles - Get to Know Them Analytically
Library Number: PSTR135088360 | Format: PDF | File Size: 1085.77 kB | Year: 2021 | Content Type: Posters

The recent success of mRNA vaccines is largely due to their ability to use human ribosomes to produce the correct protein. This was discovered multiple years prior to their Emergency Use Authorization as a vaccine. They transitioned from “promising techno...

Analysis Of Oligonucleotide Impurities On The Bioaccord LC-MS System With ACQUITY Premier
Library Number: PSTR135088374 | Format: PDF | File Size: 1086.27 kB | Year: 2021 | Content Type: Posters

Here we demonstrate the use of a novel chromatographic system, equipped with a modified surface technology across its entire fluidic path [1-2], for analysis of modified synthetic oligonucleotides and their impurities. An automated workflow, suitable for ...

Improving Performance Of Multi-Attrubute Method Assays Using An LC-MS With A Novel Inert Fludic Path...
Library Number: PSTR135088377 | Format: PDF | File Size: 1209.55 kB | Year: 2021 | Content Type: Posters

The Peptide Multi-Attribute Method (MAM) is an LC-MS assay for direct measurement of product and critical quality attribute (pQA and CQA) levels in a digest of a biotherapeutic protein. In this study, we demonstrate that MAM assay performance can be optim...

Comprehensive AAV Characterizations Using HRMS: Capsid Proteins, Empty/Full Capsid Ratio and ssDNA A...
Library Number: PSTR135088380 | Format: PDF | File Size: 1403.77 kB | Year: 2021 | Content Type: Posters

- Methods for UPLC-TOF-MS analysis of both trypsin digested AAV5 and intact capsid proteins of several AAV serotypes - Demonstrate the utility of charge-detection MS (CDMS) to analyze ssDNA isolated from AAV9 by anion-exchange chromatography (AEC) - Empt...

Polymer Separation Infographic
Library Number: MRKT135074587 | Format: PDF | File Size: 2348.42 kB | Year: 2021 | Content Type: Marketing/Online Tools

This infographic describes how by leveraging modern polymer analytical technologies, organizations can gain a competitive advantage and accelerate their materials innovation by enhancing productivity, improving processing, and meeting sustainability goals...

ACQUITY Premier with Binary Solvent Management
Library Number: LITR135080381 | Format: PDF | File Size: 133.39 kB | Year: 2021 | Content Type: Literature

Specifications for the ACQUITY Premier System with Binary Solvent Management.

ACQUITY Premier with Quaternary Solvent Management System
Library Number: LITR135080387 | Format: PDF | File Size: 131.68 kB | Year: 2021 | Content Type: Literature

Specifications for ACQUITY Premier with Quaternary Solvent Management System.

Monitoring Nutrients and Metabolites in Spent Cell Culture Media for Bioprocess Development Using th...
Library Number: APNT135088229 | Format: PDF | File Size: 1815.91 kB | Year: 2021 | Content Type: Application Notes

This application note describes a detailed reversed phase LC-MS method and a comprehensive workflow for the monitoring of compounds in cell culture media.

Routine Accurate Mass Measurement for the Identification of Impurities in Quetiapine Fumarate API Us...
Library Number: APNT135088243 | Format: PDF | File Size: 1593.7 kB | Year: 2021 | Content Type: Application Notes

This application note demonstrates a simplified workflow for routine accurate mass measurement for the identification of Quetiapine and its related impurities with the ACQUITY RDa Detector.

Rapid and Accessible Mass Detection Tools for the Identification of Substitution Fraud in Dried Herb...
Library Number: PSTR135088112 | Format: PDF | File Size: 1082.96 kB | Year: 2021 | Content Type: Posters

This poster presented at AOAC INTERNATIONAL Annual Meeting & Exposition from August 27-September 2, 2021 at Boston, USA.

Automating Preparation of Matrix-Matched Calibrants
Library Number: PSTR135088065 | Format: PDF | File Size: 1512.44 kB | Year: 2021 | Content Type: Posters

This poster presented at AOAC INTERNATIONAL Annual Meeting & Exposition from August 27-September 2, 2021 at Boston, USA.

BioAccord System with ACQUITY Premier - Instrument Specifications
Library Number: LITR135088087 | Format: PDF | File Size: 449.46 kB | Year: 2021 | Content Type: Literature

The BioAccord System is a fully integrated solution that simplifies high performance LC-MS analysis for every user. An easy-to-use system solution that puts the power to make decisions directly in your hands; a self-calibrating, self-optimizing, self-suff...