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Improved Peak Shape and Wide Selectivity Range with ACQUITY PREMIER Columns
Library Number: APNT135074676 | Format: PDF | File Size: 425.44 kB | Year: 2020 | Content Type: Application Notes

This application note demonstrate the improved peak shapes obtained for metal-sensitive analytes that were enabled using ACQUITY PREMIER Columns.

Andrew+ Pipetting Robot for Released N-Glycan Analysis
Library Number: LITR135073114 | Format: PDF | File Size: 2218.76 kB | Year: 2020 | Content Type: Literature

Waters and Andrew Alliance have developed an application-specific configuration of the Andrew+ Pipetting Robot for released N-glycan analysis.

Intact Trastuzumab Monoclonal Antibody Quantification Using the Xevo G2-XS QTof High Resolution Mass...
Library Number: APNT134994628 | Format: PDF | File Size: 1085.47 kB | Year: 2018 | Content Type: Application Notes

This technology brief demonstrates the performance of the Xevo™ G2-XS QTof platform for intact level quantification of trastuzumab monoclonal antibody and the use of UNIFI™ for rapid data processing and analysis.

A Sensitive Microflow LC-MS/MS Method for the Analysis of Fluticasone Propionate in Human Plasma
Library Number: APNT134932133 | Format: PDF | File Size: 431.95 kB | Year: 2017 | Content Type: Application Notes

This application note demonstrates the quantification of fluticasone propionate in human plasma.

Developing Analytical Chromatographic Methods for Pharmaceutical Storage Stability Investigations
Library Number: WEBC134969485 | Format: Web Page | File Size: - | Year: 2016 | Content Type: On Demand Webinar

In this on-demand webinar hosted by SelectScience, Dr. Thomas Swann talks about developing a stability indicating method capable of measuring both the drug and the degradants that may arise during pharmaceutical storage stability investigations.

Detection and Identification of Synthetic Phosphodiesterase Type-5 Inhibitors in Adulterated Herbal ...
Library Number: APNT10119959 | Format: PDF | File Size: 2731.12 kB | Year: 2015 | Content Type: Application Notes

In this work, we evaluate the use of the Xevo TQ MS for the detection and identification of adulterants in herbal supplements.

Integration of microfluidic LC with HRMS for the analysis of analytes in biofluids: past, present an...
Library Number: JOUR134851857 | Format: Web Page | File Size: - | Year: 2015 | Content Type: Journal Citations

In this article the authors describe the past, present and future of the integration of microfluidic LC with HRMS for the analysis of analytes in biofluids.

Increasing Efficiency of Method Validation with Waters Empower 3 Method Validation Manager (MVM)
Library Number: WEBC134820984 | Format: Web Page | File Size: - | Year: 2014 | Content Type: On Demand Webinar

Margaret Maziarz, Senior Scientist highlights how you can streamline your workflow throughout the entire validation process using Empower® 3 Method Validation Manager (MVM).

Favorable Conditions for Quantification of Peptides in Complex Samples by Multiple Reaction Monitori...
Library Number: APNT134608687 | Format: PDF | File Size: 1701 kB | Year: 2014 | Content Type: Application Notes

Easily achieve quantification of less than a femtomole from complex protein digest samples using a nanoACQUITY UPLC System coupled with a Xevo TQ MS.

Comprehensive investigation of the influence of acidic, basic, and organic mobile phase compositions...
Library Number: JOUR134654877 | Format: Web Page | File Size: - | Year: 2011 | Content Type: Journal Citations

In this work, we discuss the influence of acidic (pH 3), and basic (pH 10) aqueous mobile phases in conjunction with the two most common organic modifiers used in HPLC, acetonitrile and methanol, on the assay sensitivity of twenty-four probe pharmaceutica...

ACQUITY UPLC I-Class: Reduced System Dispersion and Advanced Features to Minimize Gradient Delay for...
Library Number: APNT134647238 | Format: PDF | File Size: 1349.19 kB | Year: 2011 | Content Type: Application Notes

The low dispersion characteristics of the ACQUITY UPLC I-Class System provide the highest resolution separations of any UHPLC system.

ACQUITY UPLC I-Class: Achieving the Lowest Carryover Across Different Injection Platforms
Library Number: APNT134647000 | Format: PDF | File Size: 1846.93 kB | Year: 2011 | Content Type: Application Notes

The ACQUITY UPLC I-Class Sample Manager with the flow-through needle and fixed-loop injection platforms was designed to deliver the ultimate in low carryover and leverage the performance of highly sensitive mass spectrometers.

Investigator SFC System product solution
Library Number: LITR134640023 | Format: PDF | File Size: 3481.6 kB | Year: 2012 | Content Type: Literature

With its unique capability of performing both analytical scale method development and semi-preparative scale purification on one platform, the Investigator SFC System provides the most flexible, efficient, and reliable SFC performance required for your la...

Mobility Assisted Data Independent Protein Identification
Library Number: APNT134609086 | Format: PDF | File Size: 2134.35 kB | Year: 2011 | Content Type: Application Notes

Achieve greater than 85% identification reproducibility with 1D-LC-HDMS[E]

Direct Analysis in Real time (DART) Mass Spectrometry of Adulterants in Herbal Slimming Products usi...
Library Number: APNT10201342 | Format: PDF | File Size: 3106.71 kB | Year: 2010 | Content Type: Application Notes

Use of Xevo TQ MS with a DART source enables the direct analysis of solids or liquids for simultaneous intact molecular ion and fragmentation information with rapid sample analysis.

UPLC for Bioanalysis: Retaining Productivity with High Data Quality using UPLC and RADAR
Library Number: APNT10171815 | Format: PDF | File Size: 1483.42 kB | Year: 2010 | Content Type: Application Notes

This application note demonstrates the use of UPLC/MS/MS to acquire high-quality data while maintaining laboratory productivity in bioanalysis.

Fast and Effective Optimization of MRM Methods for LC/MS/MS Analysis of Peptides
Library Number: APNT10136357 | Format: PDF | File Size: 3560.29 kB | Year: 2009 | Content Type: Application Notes

In this application note, we describe the use of Waters' innovative IntelliStart Software and its use with the ACQUITY UPLC and Xevo TQ MS systems to rapidly develop an MRM method for peptides and small proteins.