文獻資料庫


說明
質譜偵測應用電子書
資料庫編號: APNT135043301 | 格式: PDF | 檔案大小: 10845.23 kB | 年: 2019 | 內容類型: 應用手冊

本電子書收錄了諸多重要應用報告,內容說明 ACQUITY QDa 質譜偵測器以及 BioAccord 系統搭配 ACQUITY RDa 質譜偵測器運用於例行生物製藥分析以及監測用途的功能與效能。 這份資料概要的目標讀者包括生物製藥開發、製造以及 QC 領域當中,有意進一步運用質譜資料、希望加快產品上市速度,以及有意進一步提升組織生產力的相關人士。

使用四氫呋喃和超效能高分子層析結合梯度溶析進行聚合物添加劑分析研究
資料庫編號: APNT135037586 | 格式: PDF | 檔案大小: 1083.2 kB | 年: 2019 | 內容類型: 應用手冊

使用四氫呋喃和超效能高分子層析結合梯度溶析進行聚合物添加劑分析研究

使用超效能高分子層析結合四元溶劑管理器和蒸發光散射偵測技術對聚合物進行梯度溶析層析
資料庫編號: APNT135037655 | 格式: PDF | 檔案大小: 666.23 kB | 年: 2019 | 內容類型: 應用手冊

使用超效能高分子層析結合四元溶劑管理器和蒸發光散射偵測技術對聚合物進行梯度溶析層析

應用 UNIFI Natural Products Application Solution鑑別綠茶萃取物的化學成分
資料庫編號: APNT134775221 | 格式: PDF | 檔案大小: 3270.23 kB | 年: 2013 | 內容類型: 應用手冊

本應用文獻介紹了使用極致效能液相層析(UPLC),四極桿飛行時間質譜(QTof MS)以及中藥資料庫為基礎的UNIFI天然產物解決方案分析綠茶中化學成分的方法。該解決方案將實驗的收集數據、數據資料處理與中藥資料庫結合成整體的解決方案,使得複雜中藥化學成分的定性工作變得簡單、有效率,而且鑑定結果更有可信度,大大提高了工作效率,降低了對研究人員技術背景的要求。

以UNIFI Natural Products Application Solution鑑別未知傳統藥錠中的化學成分與推論可能使用的中藥成分
資料庫編號: APNT134775873 | 格式: PDF | 檔案大小: 4153.27 kB | 年: 2013 | 內容類型: 應用手冊

運用極致效能液相層析(ACQUITY UPLC I-Class)、四極桿飛行時間質譜(Xevo G2-S QTof)及 UNIFI天然產物解決方案鑑定未知中藥錠中的化學成分並推測其所含藥材。UNIFI對未知物成分鑑定和推測可能含有藥材的工作流程更簡單,並大幅提升未知中藥成分定性的準確性及效率。

運用UNIFI Natural Products Application Solution比較兩家不同製造商生產之雙黃連口服液的化學成分
資料庫編號: APNT134778856 | 格式: PDF | 檔案大小: 5571.1 kB | 年: 2013 | 內容類型: 應用手冊

此應用透過UNIFI Natural Products Application Solution所提供的二元比較工作流程,能夠以兩家不同製造商生產之雙黃連口服液為分析對象,快速準確地偵測出其中化學成分的異同之處。此解決方案讓研究人員更易於瞭解不同公司所製造之相同產品在成分方面有何差異,也讓製造商能夠更加準確地控制相同產品各批次的品質。

乳品中雙氰胺檢測的Waters完整解決方案
資料庫編號: APNT134721526 | 格式: PDF | 檔案大小: 1684.11 kB | 年: 2013 | 內容類型: 應用手冊

近日,紐西蘭牛奶及乳製品被檢測出含有低含量的有毒物質雙氰胺,紐西蘭政府已經下令禁售含有雙氰胺的奶類產品,本應用資料針對方法面臨嚴重基質干擾及雙氰胺滯留的挑戰提供解決方案。

Waters瘦肉精殘留檢驗解決方案
資料庫編號: APNT134671038 | 格式: PDF | 檔案大小: 400.74 kB | 年: 2012 | 內容類型: 應用手冊

瘦肉精分析專區,Waters做為層析質譜分析行業的領導者,再一次展現了集樣品前處理SPE產品、層析管柱產品、液相層析串聯質譜系統整體的技術優勢,在第一時間推出包含樣品前處理的解決方案。使用OASIS MCX SPE固相萃取匣結合UPLC/Xevo TQ 極致效能液相層析四極桿式串聯質譜系統,可以在5分鐘內輕鬆、快速、準確地檢測到低含量的瘦肉精類物質。

Monitoring Nutrients and Metabolites in Spent Cell Culture Media for Bioprocess Development Using th...
資料庫編號: APNT135088229 | 格式: PDF | 檔案大小: 1815.91 kB | 年: 2021 | 內容類型: 應用手冊

This application note describes a detailed reversed phase LC-MS method and a comprehensive workflow for the monitoring of compounds in cell culture media.

Routine Accurate Mass Measurement for the Identification of Impurities in Quetiapine Fumarate API Us...
資料庫編號: APNT135088243 | 格式: PDF | 檔案大小: 1593.7 kB | 年: 2021 | 內容類型: 應用手冊

This application note demonstrates a simplified workflow for routine accurate mass measurement for the identification of Quetiapine and its related impurities with the ACQUITY RDa Detector.

Analysis of Oligonucleotide Impurities on the BioAccord System with ACQUITY Premier
資料庫編號: APNT135087944 | 格式: PDF | 檔案大小: 1266.35 kB | 年: 2021 | 內容類型: 應用手冊

This application note demonstrates an automated, compliance-ready LC-MS workflow for purity analysis and intact mass confirmation of extensively modified oligonucleotides and their impurities.

Released Glycan Analysis of Erythropoietin Using the ACQUITY Premier Glycan BEH C18 AX Column and Bi...
資料庫編號: APNT135087950 | 格式: PDF | 檔案大小: 724.81 kB | 年: 2021 | 內容類型: 應用手冊

This application note evaluates a method developed using the ACQUITY Premier C18 AX Column and its ability to analyze RFMS-labeled sialylated structures.

Lipid Nanoparticle Compositional Analysis Using Charged Surface Hybrid Phenyl-Hexyl Separation With ...
資料庫編號: APNT135087972 | 格式: PDF | 檔案大小: 409.5 kB | 年: 2021 | 內容類型: 應用手冊

This application note demonstrates the advantage of a lower hydrophobicity stationary phase that bears a charged surface potential, namely the CSH Phenyl-Hexyl stationary phase

Enhanced Recovery of Released Glycans Using QuanRecovery Sample Vials with MaxPeak High Performance ...
資料庫編號: APNT135087970 | 格式: PDF | 檔案大小: 125.68 kB | 年: 2021 | 內容類型: 應用手冊

This work demonstrates how QuanRecovery Sample Vials with MaxPeak High Performance Surfaces (HPS) Technology can be used to increase recovery and stability of challenging analytes in the analysis of released glycans using HILIC-FLR/MS.

The BioAccord System With ACQUITY Premier for Improved Peptide CQA Monitoring
資料庫編號: APNT135087979 | 格式: PDF | 檔案大小: 1033.42 kB | 年: 2021 | 內容類型: 應用手冊

The application note demonstrates the performance gains of the BioAccord configured with the inert ACQUITY Premier resulting in increased peptide recovery and robust MS response.

Improving Released N-glycan Analysis in Biotherapeutic Development Using the ACQUITY Premier Solutio...
資料庫編號: APNT135084884 | 格式: PDF | 檔案大小: 748.69 kB | 年: 2021 | 內容類型: 應用手冊

This study demonstrates the new ACQUITY Premier System and Column technology improves the LC-FLR-MS data quality for released N-Glycan analysis.

Comprehending COVID-19: Distinct Identification of the SARS-CoV-2 Delta Variant Using the SARS-CoV-2...
資料庫編號: APNT135087766 | 格式: PDF | 檔案大小: 395.06 kB | 年: 2021 | 內容類型: 應用手冊

This application brief demonstrates the Delta variant mutations can still be captured using SARS-CoV-2 LC-MS Kit (RUO) SISCAPA Ab and be selectively identified and differentiated from the wildtype peptide found in the other variants of concern using chrom...

Method Development of Ten Antibiotic Compounds Using a Systematic Screening Protocol on an ACQUITY A...
資料庫編號: APNT135087733 | 格式: PDF | 檔案大小: 967.56 kB | 年: 2021 | 內容類型: 應用手冊

This application note demonstrates the benefits of a method development protocol based on a tiered screening approach, and its use towards developing a method to separate ten antibiotic compounds.

UPLC/MS Analysis of Mono-, Di- and Oligosaccharides Using ACQUITY UPLC BEH Amide Columns
資料庫編號: APNT10130636 | 格式: PDF | 檔案大小: 249.38 kB | 年: 2021 | 內容類型: 應用手冊

This application brief highlights the UPLC-MS analysis of mono-, di-,and oligosaccharides using ACQUITY UPLC BEH Amide Columns.

Batch-to-Batch Robustness of MaxPeak Premier Columns for the Analysis Dexamethasone Phosphate and Re...
資料庫編號: APNT135087660 | 格式: PDF | 檔案大小: 718.73 kB | 年: 2021 | 內容類型: 應用手冊

This application note demonstrates the robustness of MaxPeak Premier XSelect HSS T3 and XBridge BEH C18 Columns when used for the analysis of dexamethasone phosphate and related compounds.

Rapid Automated Antibody Purification Using Protein A-Coupled Magnetic Beads With Andrew+
資料庫編號: APNT135087577 | 格式: PDF | 檔案大小: 1123.78 kB | 年: 2021 | 內容類型: 應用手冊

The application note details about the rapid antibody purification protocol, which is reproducible, robust, and can extract antibodies in a high yield from cell culture media.

Recovery of Metal-Sensitive Analytes on the Arc Premier Solution: System-to-System Reproducibility a...
資料庫編號: APNT135087510 | 格式: PDF | 檔案大小: 979.8 kB | 年: 2021 | 內容類型: 應用手冊

In this study, the Arc Premier Solution will be tested with phosphorylated compounds that can interact with metallic surfaces to evaluate system-to-system performance.

Automated Sample Preparation Using Andrew+ Pipetting Robot for UPLC-MSE Identification and UPLC-MS/M...
資料庫編號: APNT135087515 | 格式: PDF | 檔案大小: 850.87 kB | 年: 2021 | 內容類型: 應用手冊

This application note on the MaxPeak High Performance Surfaces (HPS) Technology that provides a highly effective surface barrier that mitigates undesired interactions with metal surfaces and improves the analysis of phosphopeptides found in casein.

QuEChERS Extraction of Per- and Polyfluoroalkyl Substances (PFAS) from Edible Produce with Sensitive...
資料庫編號: APNT135087521 | 格式: PDF | 檔案大小: 1696.47 kB | 年: 2021 | 內容類型: 應用手冊

With a few minor adjustments to the extraction procedure, the QuEChERS based FDA Method C-010.01 was successfully used to analyze PFAS in a variety of different edible produce samples.

Modernized Impurity Analysis of the Kinase Inhibitor Imatinib by High-Resolution LC With MS-Compatib...
資料庫編號: APNT135087532 | 格式: PDF | 檔案大小: 520.99 kB | 年: 2021 | 內容類型: 應用手冊

In this application note, the charged surface hybrid phenyl column and MS-compatible mobile phases to achieve significantly higher separation efficiency and selectivity for Imatinib and nine of its related impurities