文獻資料庫


說明
質譜偵測應用電子書
資料庫編號: APNT135043301 | 格式: PDF | 檔案大小: 10845.23 kB | 年: 2019 | 內容類型: 應用手冊

本電子書收錄了諸多重要應用報告,內容說明 ACQUITY QDa 質譜偵測器以及 BioAccord 系統搭配 ACQUITY RDa 質譜偵測器運用於例行生物製藥分析以及監測用途的功能與效能。 這份資料概要的目標讀者包括生物製藥開發、製造以及 QC 領域當中,有意進一步運用質譜資料、希望加快產品上市速度,以及有意進一步提升組織生產力的相關人士。

使用四氫呋喃和超效能高分子層析結合梯度溶析進行聚合物添加劑分析研究
資料庫編號: APNT135037586 | 格式: PDF | 檔案大小: 1083.2 kB | 年: 2019 | 內容類型: 應用手冊

使用四氫呋喃和超效能高分子層析結合梯度溶析進行聚合物添加劑分析研究

使用超效能高分子層析結合四元溶劑管理器和蒸發光散射偵測技術對聚合物進行梯度溶析層析
資料庫編號: APNT135037655 | 格式: PDF | 檔案大小: 666.23 kB | 年: 2019 | 內容類型: 應用手冊

使用超效能高分子層析結合四元溶劑管理器和蒸發光散射偵測技術對聚合物進行梯度溶析層析

應用 UNIFI Natural Products Application Solution鑑別綠茶萃取物的化學成分
資料庫編號: APNT134775221 | 格式: PDF | 檔案大小: 3270.23 kB | 年: 2013 | 內容類型: 應用手冊

本應用文獻介紹了使用極致效能液相層析(UPLC),四極桿飛行時間質譜(QTof MS)以及中藥資料庫為基礎的UNIFI天然產物解決方案分析綠茶中化學成分的方法。該解決方案將實驗的收集數據、數據資料處理與中藥資料庫結合成整體的解決方案,使得複雜中藥化學成分的定性工作變得簡單、有效率,而且鑑定結果更有可信度,大大提高了工作效率,降低了對研究人員技術背景的要求。

以UNIFI Natural Products Application Solution鑑別未知傳統藥錠中的化學成分與推論可能使用的中藥成分
資料庫編號: APNT134775873 | 格式: PDF | 檔案大小: 4153.27 kB | 年: 2013 | 內容類型: 應用手冊

運用極致效能液相層析(ACQUITY UPLC I-Class)、四極桿飛行時間質譜(Xevo G2-S QTof)及 UNIFI天然產物解決方案鑑定未知中藥錠中的化學成分並推測其所含藥材。UNIFI對未知物成分鑑定和推測可能含有藥材的工作流程更簡單,並大幅提升未知中藥成分定性的準確性及效率。

運用UNIFI Natural Products Application Solution比較兩家不同製造商生產之雙黃連口服液的化學成分
資料庫編號: APNT134778856 | 格式: PDF | 檔案大小: 5571.1 kB | 年: 2013 | 內容類型: 應用手冊

此應用透過UNIFI Natural Products Application Solution所提供的二元比較工作流程,能夠以兩家不同製造商生產之雙黃連口服液為分析對象,快速準確地偵測出其中化學成分的異同之處。此解決方案讓研究人員更易於瞭解不同公司所製造之相同產品在成分方面有何差異,也讓製造商能夠更加準確地控制相同產品各批次的品質。

乳品中雙氰胺檢測的Waters完整解決方案
資料庫編號: APNT134721526 | 格式: PDF | 檔案大小: 1684.11 kB | 年: 2013 | 內容類型: 應用手冊

近日,紐西蘭牛奶及乳製品被檢測出含有低含量的有毒物質雙氰胺,紐西蘭政府已經下令禁售含有雙氰胺的奶類產品,本應用資料針對方法面臨嚴重基質干擾及雙氰胺滯留的挑戰提供解決方案。

Waters瘦肉精殘留檢驗解決方案
資料庫編號: APNT134671038 | 格式: PDF | 檔案大小: 400.74 kB | 年: 2012 | 內容類型: 應用手冊

瘦肉精分析專區,Waters做為層析質譜分析行業的領導者,再一次展現了集樣品前處理SPE產品、層析管柱產品、液相層析串聯質譜系統整體的技術優勢,在第一時間推出包含樣品前處理的解決方案。使用OASIS MCX SPE固相萃取匣結合UPLC/Xevo TQ 極致效能液相層析四極桿式串聯質譜系統,可以在5分鐘內輕鬆、快速、準確地檢測到低含量的瘦肉精類物質。

Determination of Aflatoxin M1 in Milk Using Immunoaffinity Chromatography Cleanup Coupled With UPLC ...
資料庫編號: APNT135091180 | 格式: PDF | 檔案大小: 538.99 kB | 年: 2021 | 內容類型: 應用手冊

This application note demonstrates the method suitable for monitoring compliance with regulatory limits set for AFM1 in milk globally.

Advanced Polymer Chromatography Reverse Phase Method for Polymer Additives Using Tetrahydrofuran and...
資料庫編號: APNT135091189 | 格式: PDF | 檔案大小: 1219.79 kB | 年: 2021 | 內容類型: 應用手冊

This application note describes methods to separate a blend of six polymer additives demonstrating the ability to convert methods from an older HPLC technique to the more advanced UHPLC and UPLC techniques.

Evaluation of Multivariate Calibration with RADIAN ASAP Data for the Quantitation of Edible Oil Blen...
資料庫編號: APNT135091010 | 格式: PDF | 檔案大小: 519.11 kB | 年: 2021 | 內容類型: 應用手冊

This application notes demonstrate the Blending of edible oils can improve the functional properties, stability, and sensory characteristics for the manufacturing of food products. In addition, adulteration of high-quality edible oils with cheap alternati...

LC-MS Bioanalytical Quantification of a GalNAc-siRNA Conjugate Oligonucleotide Using Semi-Automated ...
資料庫編號: APNT135090946 | 格式: PDF | 檔案大小: 785.04 kB | 年: 2021 | 內容類型: 應用手冊

This app note demonstrates the the capabilities of the Pipette+ in combination with the Otto SPEcialist for semi-automated liquid handling and solid phase extraction (SPE) of a GalNAc-siRNA conjugated oligonucleotide.

Routine Determination of Per- and Polyfluoronated Alkyl Substances (PFAS) in Drinking Water by Direc...
資料庫編號: APNT135090959 | 格式: PDF | 檔案大小: 1103.08 kB | 年: 2021 | 內容類型: 應用手冊

This application notes demonstrate a direct injection UPLC-MS/MS method for the determination of PFAS compounds in drinking water in response to the parametric level requirements in the 2020 recast EU Drinking Water Directive.1 The method performance stud...

Determination of Fatty Acids Composition in Polysorbate 20 Pharmaceutical Raw Material Using HPLC wi...
資料庫編號: APNT135087356 | 格式: PDF | 檔案大小: 744.22 kB | 年: 2021 | 內容類型: 應用手冊

This application note details about a fast HPLC method with mass detection for polysorbate 20 analysis based on free fatty acids composition.

Improvements in the Chromatographic Performance of Antiviral Compounds Analyzed with MaxPeak HPS Tec...
資料庫編號: APNT135090909 | 格式: PDF | 檔案大小: 438.96 kB | 年: 2021 | 內容類型: 應用手冊

In this application note, we compare the chromatographic performance of an XBridge Premier BEH C18 Column to the performance of a conventional XBridge BEH C18 Stainless-Steel Column for the separation of twelve representative antiviral pharmaceutical comp...

Reductions in Cost and Time by Modernizing a USP Monograph Method from HPLC to UHPLC and UPLC Instru...
資料庫編號: APNT135090912 | 格式: PDF | 檔案大小: 492.93 kB | 年: 2021 | 內容類型: 應用手冊

In this application note, we demonstrate modernization of a USP method for naproxen sodium tablets from HPLC to UHPLC and UPLC technologies.

Exceptional Carryover Performance of the Arc HPLC System for Chlorhexidine Sample
資料庫編號: APNT135090923 | 格式: PDF | 檔案大小: 1099.39 kB | 年: 2021 | 內容類型: 應用手冊

This app note demonstrates the exceptional carryover performance of Arc HPLC System for Chlorhexidine sample.

HILIC as an Alternative Separation Mode for Intact Mass Confirmation of Oligonucleotides on the BioA...
資料庫編號: APNT135090878 | 格式: PDF | 檔案大小: 1029.14 kB | 年: 2021 | 內容類型: 應用手冊

This application note demonstrates about the BioAccord LC-MS System, which enables waters_connect users to perform rapid and accurate intact mass confirmations for small and medium size oligonucleotides (up to 50-mers).

Separation of Pentose Phosphate Pathway, Glycolysis, and Energy Metabolites Using an ACQUITY Premier...
資料庫編號: APNT135090564 | 格式: PDF | 檔案大小: 1573.07 kB | 年: 2021 | 內容類型: 應用手冊

This application note describes about, the ACQUITY Premier System and Atlantis Premier BEH Z-HILIC Columns which will be useful for polar metabolomics assays, particularly for metabolites that interact with metal surfaces.

Automated RapiFluor-MS Labeled Glycan Sample Preparation for Disulfide-Rich Glycoprotein
資料庫編號: APNT135090582 | 格式: PDF | 檔案大小: 1299.77 kB | 年: 2021 | 內容類型: 應用手冊

This application note demonstrates N-glycans are routinely monitored for the quality of biotherapeutics because they affect the safety and efficacy of many therapeutic proteins. Current glycan analysis is developed with the well-studied glycans from monoc...

Utilizing the SELECT SERIES Cyclic IMS for High Throughput Plasma Proteomics
資料庫編號: APNT135090350 | 格式: PDF | 檔案大小: 653.79 kB | 年: 2021 | 內容類型: 應用手冊

This application note demonstrates, the use of analytical scale chromatography for the analysis of plasma tryptic digest samples using the SELECT SERIES Cyclic IMS, which have previously been analyzed using an alternative Q-Tof mass spectrometer.

Metrological Traceability of the Waters MassTrak Endocrine Steroid Calibrator and Quality Control Se...
資料庫編號: APNT135090210 | 格式: PDF | 檔案大小: 657.65 kB | 年: 2021 | 內容類型: 應用手冊

This application brief, provide an overview of the Waters MassTrak Endocrine Steroid Calibrator and Quality Control Sets and their accuracy and comparisons across lot-to-lot testing.

Methods for the Anion Exchange Chromatographic Analysis of mRNAs
資料庫編號: APNT135089970 | 格式: PDF | 檔案大小: 228.6 kB | 年: 2021 | 內容類型: 應用手冊

In this application note, we demonstrate that using an anion exchange column between 30–50 °C at neutral pH might be suitable for this type of analysis.

Determination of Fatty Acids in Polysorbate 80 Pharmaceutical Raw Materials by HPLC With Mass Detect...
資料庫編號: APNT135090024 | 格式: PDF | 檔案大小: 1388.71 kB | 年: 2021 | 內容類型: 應用手冊

This application note demonstrates about how an HPLC-MS was developed for the determination of fatty acids composition in the polysorbate 80 pharmaceutical raw material by direct analysis of hydrolyzed samples.

Improving Peak Capacity while Maintaining Selectivity using CORTECS Columns on an Agilent 1290 LC Sy...
資料庫編號: APNT135084109 | 格式: PDF | 檔案大小: 615.09 kB | 年: 2021 | 內容類型: 應用手冊

This application note investigates a separation of six sulfa drugs using a superficially porous CORTECS C18 Column.