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Taking Advantage of Enhanced Sensitivity of the SYNAPT XS HDMS System for the Characterization of In...
Библиотечный номер: APNT135043377 | Формат: PDF | Размер файла: 749.43 kB | Год: 2020 | Тип содержания: Методики

This application brief demonstrates the advanced sensitivity and resolution of the SYNAPT XS with a dilution series of trastuzumab in both denaturing and native states.

Utilizing an Automated Platform to Streamline Workflow Processes: Sample Preparation and Extraction ...
Библиотечный номер: APNT135073556 | Формат: PDF | Размер файла: 1516.4 kB | Год: 2020 | Тип содержания: Методики

This work aims to provide a practical and broadly applicable, automated SPE strategy for the accurate and reproducible quantification of drugs of abuse and pain management drugs from urine samples in support of clinical research in forensic toxicology.

Determination of Trace Mono-Carbonyl Compounds in E-Cigarette Aerosols by LC-MS
Библиотечный номер: APNT135073521 | Формат: PDF | Размер файла: 1542 kB | Год: 2020 | Тип содержания: Методики

This application note describes a simplified solution for the analysis of mono-carbonyls at low levels in complex aerosol sample matrices with good sensitivity and selectivity using a UPLC coupled to single quadrupole mass spectrometer (ACQUITY QDa Mass D...

Comprehending COVID-19: LC-MS/MS Analysis of Small Molecule Anti-Viral and Anti-Inflammatory Drugs i...
Библиотечный номер: APNT135073528 | Формат: PDF | Размер файла: 1278.22 kB | Год: 2020 | Тип содержания: Методики

This application note demonstrates a method for the analysis of favipiravir, remdesivir (GS-5734), GS-441524, chloroquine, hydroxychloroquine, desethylchloroquine, lopinavir, ritonavir, and dexamethasone in plasma using 50 µL of sample.

Extending the Capabilities of the BioAccord LC-MS System with a streamlined workflow for compliant-r...
Библиотечный номер: APNT135073093 | Формат: PDF | Размер файла: 694.7 kB | Год: 2020 | Тип содержания: Методики

The use of BioAccord LC-MS System combined with a novel informatics workflow for peptide MAM analysis.

Empowering You: Achieve More By Doing Less Webinar - Creating Custom Fields in Empower
Библиотечный номер: APNT135073046 | Формат: PDF | Размер файла: 396.66 kB | Год: 2020 | Тип содержания: Методики

Empower Webinar #3 Worksheet - Creating Custom Fields in Empower

Empowering You: Achieve More By Doing Less Webinar - Empower 3 Software Automated Custom Calculation...
Библиотечный номер: APNT135073049 | Формат: PDF | Размер файла: 2105.2 kB | Год: 2020 | Тип содержания: Методики

Empowering You: Achieve More By Doing Less - Empower 3 Software Automated Custom Calculations

Empowering You: Achieve More By Doing Less Webinar - Custom Fields For Assay Calculations In Food
Библиотечный номер: APNT135073054 | Формат: PDF | Размер файла: 2089.97 kB | Год: 2020 | Тип содержания: Методики

Empowering You: Achieve More By Doing Less Webinar - Custom Fields For Assay Calculations In Food

LipidQuan-R for Diacyl-Phosphatidylcholines in Human Serum: A Rapid, Targeted UPLC-MS/MS Method for ...
Библиотечный номер: APNT135073069 | Формат: PDF | Размер файла: 831.95 kB | Год: 2020 | Тип содержания: Методики

A rapid UPLC-MS/MS methodology has been developed for the specific and semi-quantitative analysis of diacyl-phosphatidylcholine species in biomedical research lipidomics studies.

Differentiation of Natural Vitamin E from Synthetic Vitamin E for Food and Dietary Supplement Nutrit...
Библиотечный номер: APNT135072984 | Формат: PDF | Размер файла: 357.87 kB | Год: 2020 | Тип содержания: Методики

This application brief demonstrates the capability of Waters ACQUITY UPC2 system and Trefoil columns for the differentiation between natural and synthetic vitamin E.

BioResolve SEC mAb Guard Columns for Production Process and Formulation Development Samples
Библиотечный номер: APNT135072999 | Формат: PDF | Размер файла: 798.68 kB | Год: 2020 | Тип содержания: Методики

This application brief demonstrates the utility of the BioResolve SEC mAb, 200 Å, 2.5 µm Guard Column to provide effective protection for an analytical BioResolve SEC, 2.5 µm, 7.8 x 300 mm Column, and having minimum impact on resolution.

Developing a Quantitative Surrogate Peptide Assay – Peptide mapping through MRM Optimization for Mea...
Библиотечный номер: APNT135072951 | Формат: PDF | Размер файла: 1174.32 kB | Год: 2020 | Тип содержания: Методики

The work herein describes a complete workflow for assay development of Fc containing therapeutics. Peptide mapping experiments were used to characterize and identify appropriate peptides for quantification.

Routine Quantitation of Polychlorinated Biphenyls (PCBs) in Sediments Using Electron Ionization GC-M...
Библиотечный номер: APNT135072928 | Формат: PDF | Размер файла: 1098.77 kB | Год: 2020 | Тип содержания: Методики

This application brief demonstrates to evaluate the Xevo™ TQ-GC as a fit for purpose electron ionization (EI) GC-MS/MS for the routine analysis of polychlorinated biphenyls (PCBs) extracted from sediment samples.

Multiresidue Method for the Quantification of Pesticides in Fruits, Vegetables, Cereals and Black Te...
Библиотечный номер: APNT135072936 | Формат: PDF | Размер файла: 903.31 kB | Год: 2020 | Тип содержания: Методики

In this application note we demonstrate a multi-residue UPLC-MS/MS method developed for the determination of 552 pesticides and relevant metabolites for pesticide residue analysis.

GlycoWorks RapiFluor-MS Automation Using the Andrew+ Pipetting Robot
Библиотечный номер: APNT135072949 | Формат: PDF | Размер файла: 864.45 kB | Год: 2020 | Тип содержания: Методики

In this application brief, the process of optimization for the 8-sample GlycoWorks RapiFluor-MS released N-glycan protocol is detailed.

Determination of Aromatic Hydrocarbon Types in Aviation Fuels and Petroleum Distillates with the All...
Библиотечный номер: APNT135072810 | Формат: PDF | Размер файла: 519.37 kB | Год: 2020 | Тип содержания: Методики

This application brief highlights the use of the Waters Alliance HPLC System coupled to the Waters 2414 Refractive Index Detector to determine mono- and di-aromatic hydrocarbon contents in petroleum distillates and aviation fuels in compliance with the AS...

How-to-Series Video 4: Application Note
Библиотечный номер: APNT135072819 | Формат: Интернет страница | Размер файла: - | Год: 2020 | Тип содержания: Методики

How To Video Episode #4 – Improve LC-MSMS performance

Determination of Chlorate and Perchlorate in Infant Milk Using Waters Anionic Polar Pesticide Column...
Библиотечный номер: APNT135035297 | Формат: PDF | Размер файла: 259.39 kB | Год: 2020 | Тип содержания: Методики

This application note evaluates the performance of the ACQUITY UPLC I-Class System, coupled with the Xevo TQ-XS Mass Spectrometer, for the determination of chlorate and perchlorate in dairy products.

Lessons from COVID-19: Verifying Performance of an HPLC-UV Method with MS-Compatible Conditions for ...
Библиотечный номер: APNT135072742 | Формат: PDF | Размер файла: 773.19 kB | Год: 2020 | Тип содержания: Методики

In this application brief we present a fast and reliable HPLC-UV method for chloroquine phosphate analysis with use of MS-compatible buffer, while meeting the USP system suitability requirements.

High Resolution Size-Exclusion Chromatography Separations of mAb Aggregates, Monomers, and Fragments...
Библиотечный номер: APNT135072714 | Формат: PDF | Размер файла: 1299.15 kB | Год: 2020 | Тип содержания: Методики

The objective of this application note is to show how LC system dispersion volume affects mAb separations based on the selected SEC column I.D. and length.

Development of a Sensitive High Resolution Mass Spectrometry Method for Quantitation of N-Nitrosamin...
Библиотечный номер: APNT135072630 | Формат: PDF | Размер файла: 1064.42 kB | Год: 2020 | Тип содержания: Методики

In this application note we demonstrate the ability to attain both sensitive and selective detection of six N-nitrosamines (NDMA, NDEA, NDIPA, NEIPA, NMBA, and NDBA) using Tof-MRM acquisition on the Xevo G2-XS QTof.

Separation and Analysis of TCA Cycle Analytes by Mixed-Mode Chromatography Coupled with Mass Spectro...
Библиотечный номер: APNT135041807 | Формат: PDF | Размер файла: 1355.55 kB | Год: 2020 | Тип содержания: Методики

A reproducible LC-MS method is described for the analysis of the TCA cycle analytes as well as other related compounds without the need for sample derivatization or ion-pairing reagents.

Method Transfer of a Fast Gradient from a Binary HPLC to an Arc HPLC System
Библиотечный номер: APNT135071981 | Формат: PDF | Размер файла: 641.05 kB | Год: 2020 | Тип содержания: Методики

This application brief demonstrates the method transfer for a fast gradient method from an HPLC legacy system to the Arc HPLC System.

Development of a Sensitive High Resolution Mass Spectrometry Method for Quantitation of N Nitrosamin...
Библиотечный номер: APNT135071818 | Формат: PDF | Размер файла: 1068.72 kB | Год: 2020 | Тип содержания: Методики

This application note demonstrates the ability to attain both sensitive and selective detection of six N-nitrosamines using Tof-MRM acquisition on the Xevo G2-XS QTof.

Comprehending COVID-19: Fast Analysis of Ribavirin and Related Compounds Using Hydrophilic Interacti...
Библиотечный номер: APNT135071822 | Формат: PDF | Размер файла: 521.06 kB | Год: 2020 | Тип содержания: Методики

This application note reports a method for the separation of ribavirin and related compounds using HILIC.