UPLC-MS/MS Determination of GLP-1 Analogue, Liraglutide A Bioactive Peptide in Human Plasma

ライブラリ番号:
APNT135019517
Part Number:
720006568EN
著者:
Tirumal A. Datar, Taposh G. PMN Rajesh, and Dr. Padmakar Wagh
カテゴリ:
Waters
コンテンツタイプ:
アプリケーション情報
コンテンツ種別:
アプリケーション情報
関連製品情報:
 
 

This application highlights a simple sample pretreatment and SPE sample preparation strategy combined with analytical flow LC and tandem quadrupole MS for the highly sensitive and reproducible analysis of liraglutide from human plasma. Protein precipitation in combination with a mixed-mode SPE performed in the μElution format eliminated the need for sample evaporation, reducing losses due to adsorption, and provided selectivity to the assay.


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