Ion-Pairing Selection and Mixer Considerations in the Development of LC-MS Workflows

Library Number:
APNT135085271
Part Number:
720007281EN
Author(s):
Robert E. Birdsall, David Dao, Brooke M. Koshel, Ying Qing Yu
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Technical Notes
Related Products:
 
 
 
 
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This study demonstrates large volume mixers provide an effective means to reduce baseline noise in UV chromatograms while maintaining MS sensitivity for RPLC-based methods that incorporate FA as an ion-pairing reagent.


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