SPE Sample Preparation for UPLC-MS Determination of Enrofloxacin (Baytril®) in Chicken

Library Number:
WA43206
Part Number:
WA43206
Author(s):
Kim vanTran, Kevin M. Jenkins, Eric S. Grumbach, Erin E. Chambers, and Michael S. Young [Waters]
Source:
LC/GC North America Applications Notebook
Content Type:
Application Notes
Content Subtype:
Application Notes
Compounds:
Enrofloxacin, Ciprofloxacin
Matrix:
Chicken
Related Products:
 
In 2005, the US FDA banned the use of the enrofloxacin (Baytril®) for growth enhancement in poultry production. Prior to this ruling, an LOQ of 10 µg/kg was appropriate for enrofloxacin residue methods. However, in light of the recent change in regulation, any detectable residue of enrofloxacin (or ciprofloxacin metabolite) can be considered evidence of inappropriate poultry farming practice. Consequently, much lower quantitation limits may be necessary.

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