SPE Sample Preparation for UPLC-MS Determination of Enrofloxacin (Baytril®) in Chicken
In 2005, the US FDA banned the use of the enrofloxacin
(Baytril®) for growth enhancement in poultry production. Prior to this
ruling, an LOQ of 10 µg/kg was appropriate for enrofloxacin residue
methods. However, in light of the recent change in regulation, any
detectable residue of enrofloxacin (or ciprofloxacin metabolite) can be
considered evidence of inappropriate poultry farming practice.
Consequently, much lower quantitation limits may be necessary.