Compound Purification Workflow Management and Optimization

Library Number:
720000696EN
Part Number:
720000696EN
Author(s):
Paul M. Lefebvre, Andrew Brailsford, David Brindle, Clare North, Ronan Cleary, Warren B. Potts III, Brian W. Smith
Source:
Pittcon 2003, Orlando, FL, March 9-14, 2003
Content Type:
Posters
Content Subtype:
Pittcon
Traditionally, drug discovery laboratories have screened large libraries with mininal to no purity requirements. Today, laboratories screen libraries that are smaller and more focused with specific purity limits, typically 85% or greater. This places a greater burden on the overall purification process. Efficiently managing this burden requires purification strategies that dovetail into the overall synthesis-to-screen process. This poster illustrates how a compound library is taken through a purification process, using the Waters AutoPurify Software.

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720000696en PDF 1178.3kB