Increased Sequence Coverage by Peptide Mass Fingerprinting using MALDI in Combination with N-Terminal Modification of Tryptic Peptides

Library Number:
720000761EN
Part Number:
720000761EN
Author(s):
Waters
Source:
Waters Poster
Content Type:
Posters
Content Subtype:
Other Symposium
Related Products:
maldi_micro_mx
Peptide mass fingerprinting (PMF) is a widely used MALDI TOF MS technique for the identification of proteins. PMF relies on the comparison of experimentally obtained peptide masses from enzymatically digested proteins with theoretical peptide masses, obtained through the in silico digestion of proteins contained within protein or translated nucleotide databanks. The most widely used enzyme is trypsin due to its availability in a pure form and compatibility with mass spectrometry.

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