Biopharmaceutical companies are increasing sample throughput demands on their analytical groups without a commensurate increase in analyst headcount. Analyst time has become a limited commodity, and many R&D groups experience delays of days to weeks for simple intact mass characterization of their molecules. Open access LC/MS provides a mechanism for organizations to leverage one analytical scientist to enable one or multiple research groups to carry out routine LC/MS analysis, with minimal or limited analyst involvement. In this poster, characteristics of an Open Access environment are explored. A system configured analysis of intact and reduced antibodies (heavy/light chain) is presented as a prototype application of open access for the biopharmaceutical environment. This poster was shown at Mass Spec 2007: Fourth Symposium on the Practical Applications of Mass Spectrometry in the Biotechnology and Pharmaceutical Industries.