Development of an Automated High Throughput UPLC/MS/MS Protocol with Multi-Mode Ionization for In-Vitro Metabolic Stability Assay

Library Number:
720001935EN
Part Number:
720001935EN
Author(s):
Kate Yu, Peter Alden, Rob Plumb, Li Di, Susan Li, Edward Kerns, Paul Chilvers
Source:
LC/MS Montreux Symposium 2006 November 8 - 10 Montreux, Switzerland
Content Type:
Posters
Content Subtype:
Montreux
This poster shows an automated ESCi-LC/MS/MS analytical protocol for the in vitro metabolic stability test using the 96 well plate to demonstrate the advantages of ESCi™ multimode ionization and the Waters ACQUITY UPLC™ for higher throughput and broader compound coverage in drug discovery.

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