Liquid Chromatography Coupled with a Mass Spectrometer Incorporating a Travelling Wave Ion Mobility Spectrometer for Analysing Complex Peptide Mixtures

Library Number:
720001735EN
Part Number:
720001735EN
Author(s):
Christopher Hughes, Steven Pringle, James Langridge, Kevin Giles, Jason Wildgoose and Robert H. Bateman
Source:
ASMS 2006 May 28-June 1, Seattle, Wa
Content Type:
Posters
Content Subtype:
ASMS
Related Products:
SYNAPT HDMS
ASMS 2006 Ion Mobility II In this poster we describe the use of an ion mobility spectrometer coupled with time-of-flight mass spectrometry for the separation and mass analysis of peptides. IMS provides an additional stage of separation and can improve signal to noise by the removal of singly charged background ions from multiply charged peptides. Post IMS fragmentation can be used to associate fragment ions with their precursor ions, providing extra specificity.

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