Clustering Precursor and its Fragmentation Data Across Multiple Samples

Library Number:
720001723EN
Part Number:
720001723EN
Author(s):
Guo-Zhong Li, Marc V. Gorenstein, Dan Golick, Richard Denny, Craig A. Dorschel, Jeffrey C. Silva, Scott J. Geromanos
Source:
ASMS 2006 May 28-June 1 Seattle, Wa
Content Type:
Posters
Content Subtype:
ASMS
ASMS 2006 Bioinformatics II_ Biomarker discovery by proteomic profilebased on LC/MSE technology needs to track ions from different samples. Here we develop algorithm to use protein ID, peptide sequence and retention time to track ions. The tracking result from replicated injections of one sample can be used for more accurate intensity measurement because that they are replicated data. The tracking result from different samples can give the expression changes (intensity changes) of the samples and lead to biomarker discovery.

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