QUANTITATIVE BIOANALYSIS BY LC/MS/MS: A COMPARISON OF UPLC AND HPLC

Library Number:
720001536EN
Part Number:
720001536EN
Author(s):
Peter G. Alden, Kate Yu, Rob Plumb
Source:
Pittcon 2006
Content Type:
Posters
Content Subtype:
Pittcon
Related Products:
This paper demonstrates the performance of the Waters Quattro Micro tandem quadrupole mass spectrometer with a Waters ACQUITY UPLC System for quantitative analysis. A drug mixture was prepared to demonstrate the improvements in quantitation attainable by combining UPLC with a tandem quadrupole mass spectrometer using electrospray ionization in both the ESI+ and polarity switching modes. The results obtained from the UPLC analysis were compared with that of HPLC analysis carried out under similar conditions.

Title Format File Size
720001536en PDF 238.64kB