A Comparison of UPLC/MS/MS and HPLC/MS/MS for Bioanalytical Method Validation Using an Analogue Internal Standard
This poster shows that the Waters UPLC combined with the Waters
Micromass Quattro Premier XE (UPLC/MS/MS) operating in MRM mode is an
accurate, precise and robust technique, which will also give the
benefits of greater speed, sensitivity and resolution over HPLC/MS/MS.
We produced a validated UPLC/MS/MS method for the analysis of Pindolol
and Acebutolol in human plasma over the range 0.2-1.50 ng/mL.