The Use of Ion Mobility Spectrometry (IMS) Coupled with Time-of-Flight Mass Spectrometry for the Study of Gas Phase Protein Conformation

Library Number:
720002143EN
Part Number:
720002143EN
Author(s):
Marc Kipping, Kevin Giles, Chris Hughes, Therese McKenna, Iain Campuzano, Jim Langridge
Source:
DGMS 2007, Mar. 11-14, University of Breman, Germany
Content Type:
Posters
Content Subtype:
Other Symposium
Related Products:
SYNAPT HDMS
We have investigated the use of the hybrid ion mobility/ time-of-flight system for the analysis of intact proteins. We have looked at proteins of different molecular masses and examined the IMS-MS data for the information that we can obtain. Here we discuss this work with examples of how IMS coupled with time-of-flight MS can be used for the systematic analysis of protein structure shown.

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