High Sensitivity Peptide Analysis Using a Novel MALDI Substrate

Library Number:
720001117EN
Part Number:
720001117EN
Author(s):
Weibin Chen, Grace M. Credo, Henry Shion, John C. Gebler
Source:
Presented at: ABRF 2005; Association of Biomolecular Resource Facilities Annual Meeting; February 5-8; Savannah GA
Content Type:
Posters
Content Subtype:
ABRF
A patterned self-assembled monolayer (SAM) that confers zones of differing wettability was constructed on a goldcoated silicon wafer to serve as a sample platform for MALDI TOF analysis. The usage of this substrate greatly increased the sensitivity of peptide analysis, resulting in 10 to 100-fold improvements compared to traditional MALDI TOF MS on a stainless steel plate.

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