Analysis of Drugs in Blood to Support the UK Section 5 Driving Under the Influence of Drugs Act

Library Number:
APNT135091346
Part Number:
720007451EN
Author(s):
Michelle Wood, Robert Lee
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notes
Related Products:
 
 
Forensic Toxicology
 
 

This appication note demonstrate the increased testing for drugs in drivers has highlighted the need for quick, accurate, reliable, and robust methods to quantify these compounds. This note details a complete workflow that can be used to determine a large panel of drugs from whole blood using the Ostro Pass-Through Sample Preparation Plate. The described procedure utilizes just 100 µL of blood which is beneficial as the amount of available sample can be limited, particularly if the sample requires multiple analyses.

The excellent sensitivity of the Xevo TQ-S micro Mass Spectrometer allows for the analytes to be detected at concentrations relevant to the legislation, while the use of the Ostro Plate allows the sample preparation protocol to be automated for any laboratories requiring higher sample throughput.


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