Quantitative Analysis of Polysorbate 20/80 in Protein-Based Biopharmaceuticals Using A One-Pot RPLC-MS Based Platform Method

Library Number:
APNT135084454
Part Number:
720007249EN
Author(s):
Robert E. Birdsall, David Dao, Brooke M. Koshel, Ying Qing Yu, Aude Smeets, Michel Gerodez, Xavier Taillieu
Source:
Waters, GlaxoSmithKline
Content Type:
Application Notes
Content Subtype:
Application Notes
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This application note demonstrates an LC-MS-based hydrolysis method can be successfully deployed to detect polysorbate constituents at sub-ppm levels using a single quad mass spectrometer.


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