Increasing Recovery and Chromatographic Performance of “Acidic” Peptides Using Waters ACQUITY PREMIER Solution

Library Number:
APNT135082322
Part Number:
720007173EN
Author(s):
Robert E. Birdsall, Jacob Kellet, Samantha Ippoliti, Ying Qing Yu
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Technical Notes
Related Products:
 
Biopharmaceutical
 
 
 
 
 
 
 

Non-specific adsorption of analytes when using conventional LC systems configured with stainless-steel hardware can lead to reduced sample recovery and poor peak shape. The Waters ACQUITY PREMIER Solution featuring MaxPeak High Performance Surfaces addresses the challenges associated with non-specific adsorption resulting in improved recovery, peak shape, and reproducibility of sensitive analytes. The benefits of ACQUITY PREMIER with MaxPeak HPS technology enable scientists to increase productivity in the lab and mitigate risk through increased reproducibility, recovery, and robustness of assays performed in the development and manufacturing of biopharmaceutical drug products.


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