A Complete Workflow for the Determination of Drugs that Conforms to the Society of Hair Testing (SoHT) Guidelines

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Robert Lee, Massimo Gottardi, Andrea Gardumi, Simone Donzelli, Michelle Wood
Waters, Comedical
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Technical Notes
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This application brief details a workflow that can be used to quantify a panel of drugs at cut-off concentrations recommended by both the SoHT and EWDTS from a single hair specimen using a commercially available extraction buffer and OASIS PRiME MCX 96-Well Plate. In combination with the ACQUITY UPLC I-Class System and Xevo TQ-S micro Mass Spectrometer, it is possible to quantify a large number of compounds at low concentrations, ensuring high sample throughput.

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